| Gene Symbol |
CDC37
|
| Entrez Gene |
11140
|
| Alt Symbol |
P50CDC37
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cell division cycle 37
|
| Other Description |
CDC37 (cell division cycle 37, S. cerevisiae, homolog)|CDC37 cell division cycle 37 homolog|cell division cycle 37 homolog|hsp90 chaperone protein kinase-targeting subunit|hsp90 co-chaperone Cdc37
|
| Swissprots |
Q16543 Q53YA2
|
| Accessions |
AAW34362 EAW84101 EAW84102 EAW84103 Q16543 AM393285 CAL38163 AM393349 CAL38227 BC000083 AAH00083 BC008793 AAH08793 BC127212 AAI27213 BC127213 AAI27214 BC141928 AAI41929 BC141929 AAI41930 BE796008 BT006796 AAP35442 CR542249 CAG47045 DQ892174 ABM83100 DQ895369 ABM86295 U43077 AAB63979 U63131 AAB04798 XM_011527652 XP_011525954 NM_007065 NP_008996
|
| Function |
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. {ECO:0000269|PubMed:8666233}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:9482106}.
|
| Top Pathways |
PI3K-Akt signaling pathway
|
![Western Blot: CDC37 Overexpression Lysate (Adult Normal) [NBL1-09002] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CDC37.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3867_CDC37%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09002-img0002.jpg)