Gene Symbol | UQCRQ |
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Entrez Gene | 27089 |
Alt Symbol | MC3DN4, QCR8, QP-C, QPC, UQCR7 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa |
Other Description | complex III subunit 8|complex III subunit VIII|cytochrome b-c1 complex subunit 8|low molecular mass ubiquinone-binding protein (9.5kD)|ubiquinol-cytochrome c reductase complex 9.5 kDa protein|ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C |
Swissprots | Q5FVE2 O14949 Q9BV88 Q9T2V7 |
Accessions | EAW62308 O14949 AK297061 BAH12487 AK312148 AW327741 BC001390 AAH01390 BC064949 BC090048 AAH90048 BG678118 BU190580 BU953465 CR743513 NM_014402 NP_055217 |
Function | This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone. |
Subcellular Location | Mitochondrion inner membrane. |
Top Pathways | Alzheimer's disease, Huntington's disease, Cardiac muscle contraction, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
QP-C CRISPR/Cas9 KO Plasmid (h) - sc-408858 from Santa Cruz Biotechnology
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QP-C HDR Plasmid (h) - sc-408858-HDR from Santa Cruz Biotechnology
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QP-C Double Nickase Plasmid (h) - sc-408858-NIC from Santa Cruz Biotechnology
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QP-C Double Nickase Plasmid (h2) - sc-408858-NIC-2 from Santa Cruz Biotechnology
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QP-C CRISPR Activation Plasmid (h) - sc-408858-ACT from Santa Cruz Biotechnology
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QP-C CRISPR Activation Plasmid (h2) - sc-408858-ACT-2 from Santa Cruz Biotechnology
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QP-C Lentiviral Activation Particles (h) - sc-408858-LAC from Santa Cruz Biotechnology
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QP-C Lentiviral Activation Particles (h2) - sc-408858-LAC-2 from Santa Cruz Biotechnology
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QP-C siRNA (h) - sc-76305 from Santa Cruz Biotechnology
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QP-C shRNA Plasmid (h) - sc-76305-SH from Santa Cruz Biotechnology
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QP-C shRNA (h) Lentiviral Particles - sc-76305-V from Santa Cruz Biotechnology
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UQCRQ RNAi - H00027089-R01 from Novus Biologicals
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MISSION® esiRNA - EHU122391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22538 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22538 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08832 from Sigma-Aldrich
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UQCRQ siRNA (Human) - CRH8956 from Cohesion Biosciences
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UQCRQ - MBS8209527 from MyBioSource
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shRNA set against Human UQCRQ (NM_014402.4) - SHH440984 from Creative biogene
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shRNA set against Human UQCRQ(NM_014402.4) - SHL116334 from Creative biogene
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UQCRQ shRNA Plasmid (Human) - CHH8956 from Cohesion Biosciences
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UQCRQ miRNA 3'UTR clone - MiUTR1H-11035 from Creative biogene
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