Gene Symbol | IRAK1BP1 |
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Entrez Gene | 134728 |
Alt Symbol | AIP70, SIMPL |
Species | Human |
Gene Type | protein-coding |
Description | interleukin-1 receptor-associated kinase 1 binding protein 1 |
Other Description | ActA binding protein 3|IRAK1-binding protein 1|interleukin-1 receptor-associated kinase 1-binding protein 1 |
Swissprots | Q5VVH5 |
Accessions | EAW48721 Q5VVH5 AK096861 AK098678 AK309003 BC112253 AAI12254 BC112255 AAI12256 BX103697 CB321683 CR990080 XM_006715336 XP_006715399 XM_011535447 XP_011533749 XM_011535448 XP_011533750 XR_942279 NM_001010844 NP_001010844 |
Function | Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. Acts by enhancing RELA transcriptional activity (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
SIMPL CRISPR/Cas9 KO Plasmid (h) - sc-407437 from Santa Cruz Biotechnology
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SIMPL HDR Plasmid (h) - sc-407437-HDR from Santa Cruz Biotechnology
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SIMPL Double Nickase Plasmid (h) - sc-407437-NIC from Santa Cruz Biotechnology
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SIMPL Double Nickase Plasmid (h2) - sc-407437-NIC-2 from Santa Cruz Biotechnology
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SIMPL CRISPR Activation Plasmid (h) - sc-407437-ACT from Santa Cruz Biotechnology
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SIMPL CRISPR Activation Plasmid (h2) - sc-407437-ACT-2 from Santa Cruz Biotechnology
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SIMPL Lentiviral Activation Particles (h) - sc-407437-LAC from Santa Cruz Biotechnology
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SIMPL Lentiviral Activation Particles (h2) - sc-407437-LAC-2 from Santa Cruz Biotechnology
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SIMPL siRNA (h) - sc-95101 from Santa Cruz Biotechnology
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SIMPL shRNA Plasmid (h) - sc-95101-SH from Santa Cruz Biotechnology
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SIMPL shRNA (h) Lentiviral Particles - sc-95101-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU018381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10760 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10760 from Sigma-Aldrich
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IRAK1BP1 siRNA (Human) - CRJ5153 from Cohesion Biosciences
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IRAK1BP1 - MBS8222966 from MyBioSource
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shRNA set against Human IRAK1BP1 (NM_001010844.1) - SHH320497 from Creative biogene
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Human IRAK1BP1 siRNA - orb275654 from Biorbyt
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IRAK1BP1 shRNA Plasmid (Human) - CHJ5153 from Cohesion Biosciences
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IRAK1BP1 miRNA 3'UTR clone - MiUTR1H-04986 from Creative biogene
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