Gene Symbol | ATP6V0C |
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Entrez Gene | 527 |
Alt Symbol | ATP6C, ATP6L, ATPL, VATL, VPPC, Vma3 |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c |
Other Description | H(+)-transporting two-sector ATPase, 16 kDa subunit|V-ATPase 16 kDa proteolipid subunit|V-type proton ATPase 16 kDa proteolipid subunit|vacuolar ATP synthase 16 kDa proteolipid subunit|vacuolar H+ ATPase proton channel subunit|vacuolar proton pump 16 kDa proteolipid subunit |
Swissprots | P27449 Q6FH26 |
Accessions | BAC06442 EAW85501 P27449 AW161158 BC004537 AAH04537 BC007389 AAH07389 BC007759 AAH07759 BC009290 AAH09290 BI548787 BT007155 AAP35819 CR541930 CAG46728 CR541951 CAG46749 JF432559 ADZ15776 JF432578 ADZ15795 M62762 AAA60039 NM_001198569 NP_001185498 NM_001694 NP_001685 |
Function | Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
Subcellular Location | Vacuole membrane; Multi-pass membrane protein. |
Top Pathways | Collecting duct acid secretion, Tuberculosis, Synaptic vesicle cycle, Rheumatoid arthritis, Phagosome |
ATP6L CRISPR/Cas9 KO Plasmid (h) - sc-406730 from Santa Cruz Biotechnology
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ATP6L HDR Plasmid (h) - sc-406730-HDR from Santa Cruz Biotechnology
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ATP6L Double Nickase Plasmid (h) - sc-406730-NIC from Santa Cruz Biotechnology
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ATP6L Double Nickase Plasmid (h2) - sc-406730-NIC-2 from Santa Cruz Biotechnology
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ATP6L CRISPR Activation Plasmid (h) - sc-406730-ACT from Santa Cruz Biotechnology
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ATP6L CRISPR Activation Plasmid (h2) - sc-406730-ACT-2 from Santa Cruz Biotechnology
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ATP6L Lentiviral Activation Particles (h) - sc-406730-LAC from Santa Cruz Biotechnology
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ATP6L Lentiviral Activation Particles (h2) - sc-406730-LAC-2 from Santa Cruz Biotechnology
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ATP6L siRNA (h) - sc-93494 from Santa Cruz Biotechnology
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ATP6L shRNA Plasmid (h) - sc-93494-SH from Santa Cruz Biotechnology
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ATP6L shRNA (h) Lentiviral Particles - sc-93494-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU023041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3721 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3721 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05007 from Sigma-Aldrich
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ATP6V0C siRNA (Human) - CRH0365 from Cohesion Biosciences
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ATP6V0C RNAi - H00000527-R02 from Novus Biologicals
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ATP6V0C - MBS8237612 from MyBioSource
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Human ATP6V0C siRNA - orb260867 from Biorbyt
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ATP6V0C shRNA Plasmid (Human) - CHH0365 from Cohesion Biosciences
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ATP6V0C miRNA 3'UTR clone - MiUTR3H-00222 from Creative biogene
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