Gene Symbol | P3H2 |
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Entrez Gene | 55214 |
Alt Symbol | LEPREL1, MCVD, MLAT4 |
Species | Human |
Gene Type | protein-coding |
Description | prolyl 3-hydroxylase 2 |
Other Description | leprecan-like 1|myxoid liposarcoma-associated protein 4|prolyl 3-hydroxylase 3 |
Swissprots | Q9NVI2 B3KPK0 B3KWI9 Q8IVL5 D3DNV8 |
Accessions | CDM55389 CDM55570 EAW78109 EAW78110 EAW78111 Q8IVL5 AJ430351 CAD23039 AK001580 BAA91769 AK056447 BAG51712 AK125134 BAG54151 BC005029 AAH05029 BU621129 BU737886 DA720646 DA879789 JF432541 ADZ15758 XM_011512955 XP_011511257 NM_001134418 NP_001127890 NM_018192 NP_060662 |
Function | Shows prolyl 3-hydroxylase activity catalyzing the post- translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types II, IV and V. {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum {ECO:0000255|PROSITE- ProRule:PRU10138, ECO:0000269|PubMed:15063763}. Golgi apparatus {ECO:0000269|PubMed:15063763}. |
Tissue Specificity | Expressed in heart, placenta, lung, liver, skeletal muscle and kidney. Expression localized to the epithelia of bile ducts and to the sacroplasm of heart muscle and skeletal muscle. In the pancreas, localized to a subpopulation of Langerhans islet cells and in the salivary gland, expressed in acinar cells. {ECO:0000269|PubMed:15063763}. |
LEPREL1 (H-4) - sc-377096 from Santa Cruz Biotechnology
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LEPREL1 (H-126) - sc-292343 from Santa Cruz Biotechnology
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LEPREL1 (B-9) - sc-377353 from Santa Cruz Biotechnology
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LEPREL1 (N-14) - sc-102652 from Santa Cruz Biotechnology
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LEPREL1 (P-12) - sc-102653 from Santa Cruz Biotechnology
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Anti-LEPREL1 antibody - ab121270 from Abcam
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Anti-LEPREL1 antibody - ab121393 from Abcam
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Anti-P3H2 / LEPREL1 Antibody - LS-C332059 from LifeSpan Bioscience
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Anti-P3H2 / LEPREL1 Antibody (aa233-399) - LS-C179132 from LifeSpan Bioscience
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LEPREL1 Antibody - NBP1-94041 from Novus Biologicals
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LEPREL1 Antibody - NBP1-94042 from Novus Biologicals
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Anti-LEPREL1 antibody produced in rabbit - HPA007890 from Sigma-Aldrich
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Anti-LEPREL1 antibody produced in rabbit - HPA013355 from Sigma-Aldrich
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LEPREL1 antibody - orb78379 from Biorbyt
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LEPREL1 antibody - orb184901 from Biorbyt
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LEPREL1 antibody - 70R-18252 from Fitzgerald
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Anti -LEPREL1 (Leprecan Like Protein 1, MCVD, P3H2, MLAT4) - 211743 from USBiological Life Science
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LEPREL1 Polyclonal Antibody - A2319 from ABclonal
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LEPREL1 antibody - 70R-35573 from Fitzgerald
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LEPREL1 Antibody - abx036203 from Abbexa
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LEPREL1 Antibody - abx001882 from Abbexa
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Prolyl 3-hydroxylase 2 antibody - 15723-1-AP from Acris Antibodies
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Anti-LEPREL1, Polyclonal Antibody - 25-A2319 from ARP American Research Products
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LEPREL1 antibody - STJ24395 from St John's Laboratory Ltd
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P3H2 antibody - 15723-1-AP from Proteintech Group
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