Gene Symbol | SLC25A31 |
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Entrez Gene | 83447 |
Alt Symbol | AAC4, ANT4, SFEC35kDa |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 |
Other Description | ADP,ATP carrier protein 4|ADP/ATP translocase 4|ANT 4|adenine nucleotide translocase 4|adenine nucleotide translocator 4|solute carrier family 25 member 31|sperm flagellar energy carrier protein |
Swissprots | Q9H0C2 |
Accessions | AAY40974 EAX05199 EAX05200 Q9H0C2 AJ863129 CAI05952 AL136857 CAB66791 AM393262 CAL38140 AY550240 AAT42263 BC022032 AAH22032 BG773445 XM_011532297 XP_011530599 XM_011532298 XP_011530600 NM_031291 NP_112581 |
Function | Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility. {ECO:0000269|PubMed:17137571}. |
Subcellular Location | Mitochondrion inner membrane; Multi-pass membrane protein. Cell projection, cilium, flagellum. Note=In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region. |
Tissue Specificity | Expressed in brain, liver, sperm and testis. {ECO:0000269|PubMed:15670820, ECO:0000269|PubMed:17137571}. |
Top Pathways | Huntington's disease, Calcium signaling pathway, HTLV-I infection, cGMP-PKG signaling pathway |
ANT4 CRISPR/Cas9 KO Plasmid (h) - sc-413468 from Santa Cruz Biotechnology
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ANT4 HDR Plasmid (h) - sc-413468-HDR from Santa Cruz Biotechnology
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ANT4 Double Nickase Plasmid (h) - sc-413468-NIC from Santa Cruz Biotechnology
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ANT4 Double Nickase Plasmid (h2) - sc-413468-NIC-2 from Santa Cruz Biotechnology
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ANT4 CRISPR Activation Plasmid (h) - sc-413468-ACT from Santa Cruz Biotechnology
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ANT4 CRISPR Activation Plasmid (h2) - sc-413468-ACT-2 from Santa Cruz Biotechnology
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ANT4 Lentiviral Activation Particles (h) - sc-413468-LAC from Santa Cruz Biotechnology
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ANT4 Lentiviral Activation Particles (h2) - sc-413468-LAC-2 from Santa Cruz Biotechnology
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ANT4 siRNA (h) - sc-88900 from Santa Cruz Biotechnology
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ANT4 shRNA Plasmid (h) - sc-88900-SH from Santa Cruz Biotechnology
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ANT4 shRNA (h) Lentiviral Particles - sc-88900-V from Santa Cruz Biotechnology
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SLC25A31 RNAi - H00083447-R01 from Novus Biologicals
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MISSION® esiRNA - EHU037891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19501 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06431 from Sigma-Aldrich
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SLC25A31 siRNA (Human) - CRJ3101 from Cohesion Biosciences
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SLC25A31 - MBS8225530 from MyBioSource
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shRNA set against Human SLC25A31 (NM_031291.2) - SHH409668 from Creative biogene
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Human SLC25A31 siRNA - orb273602 from Biorbyt
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SLC25A31 shRNA Plasmid (Human) - CHJ3101 from Cohesion Biosciences
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SLC25A31 miRNA 3'UTR clone - MiUTR3H-11472 from Creative biogene
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