| Gene Symbol |
PSMC1
|
| Entrez Gene |
5700
|
| Alt Symbol |
P26S4, S4, p56
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
proteasome (prosome, macropain) 26S subunit, ATPase, 1
|
| Other Description |
26S protease regulatory subunit 4|26S proteasome AAA-ATPase subunit RPT2|proteasome 26S ATPase subunit 1|proteasome 26S subunit ATPase 1|proteasome 26S subunit, ATPase, 1
|
| Swissprots |
Q6IAW0 Q6NW36 Q03527 P62191 P49014 B4DR63 Q96AZ3
|
| Accessions |
EAW81419 EAW81420 EAW81421 P62191 AB451311 BAG70125 AB451441 BAG70255 AF401213 AK124201 AK222668 BAD96388 AK299121 BAG61175 AK313325 BAG36130 BC000512 AAH00512 BC016368 AAH16368 BC018859 BC067741 AAH67741 BC073818 AAH73818 BT009826 AAP88828 CR457044 CAG33325 DQ185033 DQ891703 ABM82629 DQ894881 ABM85807 L02426 AAA35484 NM_002802 NP_002793
|
| Function |
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
|
| Subcellular Location |
Cytoplasm. Nucleus.
|
| Top Pathways |
Proteasome, Viral carcinogenesis, Epstein-Barr virus infection
|
![Western Blot: Proteasome 19S S4 Overexpression Lysate (Adult Normal) [NBL1-14886] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Proteasome 19S S4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9011_Proteasome%252019S%2520S4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14886-img0002.jpg)