| Gene Symbol |
GLE1
|
| Entrez Gene |
2733
|
| Alt Symbol |
GLE1L, LCCS, LCCS1, hGLE1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
GLE1 RNA export mediator
|
| Other Description |
GLE1 RNA export mediator homolog|GLE1-like protein|GLE1-like, RNA export mediator|nucleoporin GLE1
|
| Swissprots |
Q8NCP6 Q53GT9 Q53GS7 Q9UFL6 Q5VVU1 O75458
|
| Accessions |
CAE89752 EAW87802 EAW87803 EAW87804 Q53GS7 AA806769 AF058922 AAC25561 AK001767 BAG50972 AK074801 AK222842 BAD96562 AK222854 BAD96574 AK290533 BAF83222 AL117584 CAB56006 BC030012 AAH30012 BM786801 DQ895309 ABM86235 EU176245 ABW03696 XM_006717059 XP_006717122 XM_006717060 XP_006717123 XM_011518549 XP_011516851 XM_011518550 XP_011516852 XM_011518551 XP_011516853 XM_011518552 XP_011516854 NM_001003722 NP_001003722 NM_001499 NP_001490
|
| Function |
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC). {ECO:0000269|PubMed:12668658, ECO:0000269|PubMed:16000379, ECO:0000269|PubMed:9618489}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:12668658}. Cytoplasm {ECO:0000269|PubMed:12668658}. Note=Shuttles between the nucleus and the cytoplasm. Shuttling is essential for its mRNA export function.
|