| Gene Symbol |
TMEM59L
|
| Entrez Gene |
25789
|
| Alt Symbol |
BSMAP, C19orf4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane protein 59-like
|
| Other Description |
brain-specific membrane-anchored protein
|
| Swissprots |
Q9UK28
|
| Accessions |
EAW84726 EAW84727 Q9UK28 AF186264 AAF00529 AK309384 BC010446 AAH10446 BI752768 EU831798 ACE87316 EU831875 ACE86634 XM_006722719 XP_006722782 NM_012109 NP_036241
|
| Function |
Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding. {ECO:0000269|PubMed:20427278}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000305|PubMed:20427278}; Single-pass type I membrane protein {ECO:0000305|PubMed:20427278}.
|
| Tissue Specificity |
Expressed preferentially at high level in the brain.
|