Gene Symbol | ALDH1A2 |
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Entrez Gene | 8854 |
Alt Symbol | RALDH(II), RALDH2, RALDH2-T |
Species | Human |
Gene Type | protein-coding |
Description | aldehyde dehydrogenase 1 family, member A2 |
Other Description | RALDH 2|retinal dehydrogenase 2|retinaldehyde-specific dehydrogenase type 2 |
Swissprots | F5H2Y9 Q9UBR8 H0YM00 O94788 B4DZR2 B3KY52 Q2PJS6 Q8NHQ4 Q9UFY0 |
Accessions | ABC40749 BAA34788 EAW77528 EAW77529 EAW77530 O94788 AA447978 AB015226 BAA34785 AB015227 BAA34786 AB015228 BAA34787 AK128709 BAG54714 AK294981 BAG58050 AK303057 BAG64174 AL110274 AL110299 CAB53740 AL137418 BC030589 AAH30589 BI459110 BX443600 DB458699 DQ891568 ABM82494 DQ894760 ABM85686 NM_001206897 NP_001193826 NM_003888 NP_003879 NM_170696 NP_733797 NM_170697 NP_733798 |
Function | Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. |
Top Pathways | Retinol metabolism |
ALDH1A2 CRISPR/Cas9 KO Plasmid (h) - sc-401340 from Santa Cruz Biotechnology
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ALDH1A2 HDR Plasmid (h) - sc-401340-HDR from Santa Cruz Biotechnology
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ALDH1A2 Double Nickase Plasmid (h) - sc-401340-NIC from Santa Cruz Biotechnology
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ALDH1A2 Double Nickase Plasmid (h2) - sc-401340-NIC-2 from Santa Cruz Biotechnology
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ALDH1A2 CRISPR Activation Plasmid (h) - sc-401340-ACT from Santa Cruz Biotechnology
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ALDH1A2 CRISPR Activation Plasmid (h2) - sc-401340-ACT-2 from Santa Cruz Biotechnology
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ALDH1A2 Lentiviral Activation Particles (h) - sc-401340-LAC from Santa Cruz Biotechnology
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ALDH1A2 Lentiviral Activation Particles (h2) - sc-401340-LAC-2 from Santa Cruz Biotechnology
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ALDH1A2 siRNA (h) - sc-41443 from Santa Cruz Biotechnology
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ALDH1A2 shRNA Plasmid (h) - sc-41443-SH from Santa Cruz Biotechnology
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ALDH1A2 shRNA (h) Lentiviral Particles - sc-41443-V from Santa Cruz Biotechnology
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ALDH1A2 RNAi - H00008854-R02 from Novus Biologicals
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ALDH1A2 RNAi - H00008854-R03 from Novus Biologicals
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ALDH1A2 RNAi - H00008854-R01 from Novus Biologicals
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MISSION® esiRNA - EHU135351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3044 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3044 from Sigma-Aldrich
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ALDH1A2 siRNA (Human) - CRH5847 from Cohesion Biosciences
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ALDH1A2 siRNA (T. guttata) - sc-270584 from Santa Cruz Biotechnology
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ALDH1A2 shRNA Plasmid (T. guttata) - sc-270584-SH from Santa Cruz Biotechnology
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ALDH1A2 - MBS8239470 from MyBioSource
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shRNA set against Human ALDH1A2 (NM_003888.3) - SHH234802 from Creative biogene
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Human ALDH1A2 siRNA - orb266349 from Biorbyt
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ALDH1A2 shRNA Plasmid (Human) - CHH5847 from Cohesion Biosciences
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ALDH1A2 miRNA 3'UTR clone - MiUTR3H-06179 from Creative biogene
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