| Gene Symbol | PSMB1 |
|---|---|
| Entrez Gene | 5689 |
| Alt Symbol | HC5, PMSB1, PSC5 |
| Species | Human |
| Gene Type | protein-coding |
| Description | proteasome (prosome, macropain) subunit, beta type, 1 |
| Other Description | macropain subunit C5|multicatalytic endopeptidase complex subunit C5|proteasome beta 1 subunit|proteasome component C5|proteasome gamma chain|proteasome subunit HC5|proteasome subunit beta type-1 |
| Swissprots | B5BU76 Q9BWA8 P20618 |
| Accessions | EAW47420 EAW47421 EAW47422 EAW47423 P20618 AB209078 BAD92315 AB451312 BAG70126 AB451442 BAG70256 AK023290 AK058050 AK223193 BAD96913 BC000508 AAH00508 BC020807 AAH20807 BP369175 BQ685374 BT019720 AAV38525 D00761 BAA00658 EU176329 ABW03780 EU176672 ABW03473 NM_002793 NP_002784 |
| Function | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. |
| Subcellular Location | Cytoplasm. Nucleus. |
| Top Pathways | Proteasome |
20S Proteasome β1 siRNA (h) - sc-62864 from Santa Cruz Biotechnology
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20S Proteasome β1 shRNA Plasmid (h) - sc-62864-SH from Santa Cruz Biotechnology
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20S Proteasome β1 shRNA (h) Lentiviral Particles - sc-62864-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU024071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17596 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17596 from Sigma-Aldrich
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PSMB1 siRNA (Human) - CRH3836 from Cohesion Biosciences
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shRNA set against Human PSMB1 (NM_002793.3) - SHH385132 from Creative biogene
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Human PSMB1 siRNA - orb264338 from Biorbyt
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PSMB1 shRNA Plasmid (Human) - CHH3836 from Cohesion Biosciences
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PSMB1 miRNA 3'UTR clone - MiUTR3H-04601 from Creative biogene
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