Gene Symbol | TFR2 |
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Entrez Gene | 7036 |
Alt Symbol | HFE3, TFRC2 |
Species | Human |
Gene Type | protein-coding |
Description | transferrin receptor 2 |
Other Description | transferrin receptor protein 2 |
Swissprots | A6NGM7 Q1HE13 Q9NX67 Q9UP52 Q9HA99 O75422 |
Accessions | ABF47099 EAW76506 EAW76507 EAW76508 EAW76509 EAW76510 Q9UP52 AF067864 AAD45561 AF085928 AK000421 BAA91153 AK022002 BAB13951 BC142630 AAI42631 BC150192 AAI50193 BI917390 BX384750 DR004213 XM_005250553 XP_005250610 XM_005250554 XP_005250611 NM_001206855 NP_001193784 NM_003227 NP_003218 |
Function | Mediates cellular uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. |
Subcellular Location | Cell membrane; Single-pass type II membrane protein. |
Tissue Specificity | Predominantly expressed in liver. While the alpha form is also expressed in spleen, lung, muscle, prostate and peripheral blood mononuclear cells, the beta form is expressed in all tissues tested, albeit weakly. |
TFR2 CRISPR/Cas9 KO Plasmid (h) - sc-401216 from Santa Cruz Biotechnology
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TFR2 HDR Plasmid (h) - sc-401216-HDR from Santa Cruz Biotechnology
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TFR2 Double Nickase Plasmid (h) - sc-401216-NIC from Santa Cruz Biotechnology
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TFR2 Double Nickase Plasmid (h2) - sc-401216-NIC-2 from Santa Cruz Biotechnology
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TFR2 CRISPR Activation Plasmid (h) - sc-401216-ACT from Santa Cruz Biotechnology
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TFR2 CRISPR Activation Plasmid (h2) - sc-401216-ACT-2 from Santa Cruz Biotechnology
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TFR2 Lentiviral Activation Particles (h) - sc-401216-LAC from Santa Cruz Biotechnology
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TFR2 Lentiviral Activation Particles (h2) - sc-401216-LAC-2 from Santa Cruz Biotechnology
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TFR2 siRNA (h) - sc-42997 from Santa Cruz Biotechnology
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TFR2 shRNA Plasmid (h) - sc-42997-SH from Santa Cruz Biotechnology
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TFR2 shRNA (h) Lentiviral Particles - sc-42997-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN21267 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21267 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03901 from Sigma-Aldrich
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TFR2 siRNA (Human) - CRH4809 from Cohesion Biosciences
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TFR2 - MBS829064 from MyBioSource
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shRNA set against Human TF (NM_003227.3) - SHH426060 from Creative biogene
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shRNA set against Human TFR2(NM_003227.3) - SHL067350 from Creative biogene
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TFR2 shRNA Plasmid (Human) - CHH4809 from Cohesion Biosciences
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TFR2 miRNA 3'UTR clone - MiUTR1H-10347 from Creative biogene
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