Gene Symbol |
COMMD7
|
Entrez Gene |
149951
|
Alt Symbol |
C20orf92, dJ1085F17.3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
COMM domain containing 7
|
Other Description |
COMM domain-containing protein 7
|
Swissprots |
B3KTZ2 Q9BW53 Q5JYB0 A2BHJ2 Q86VX2 Q96SI7
|
Accessions |
EAW76357 EAW76358 EAW76359 EAW76360 EAW76361 EAW76362 EAW76363 EAW76364 Q86VX2 AJ012490 AK027893 BAB55436 AK096307 BAG53254 AK097059 AY542162 AAS22244 BC000628 AAH00628 BC022073 BC047440 AAH47440 BG715846 BQ006261 DN993528 XM_005260299 XP_005260356 XM_005260300 XP_005260357 XM_011528604 XP_011526906 NM_001099339 NP_001092809 NM_053041 NP_444269
|
Function |
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Associates with the NF-kappa-B complex and suppresses its transcriptional activity (PubMed:15799966). {ECO:0000269|PubMed:15799966, ECO:0000305|PubMed:21778237}.
|
Subcellular Location |
Cytoplasmic vesicle {ECO:0000269|PubMed:21778237}.
|
Tissue Specificity |
Widely expressed with highest expression in lung. {ECO:0000269|PubMed:15799966}.
|