Gene Symbol | P2RX6 |
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Entrez Gene | 9127 |
Alt Symbol | P2RXL1, P2X6, P2XM |
Species | Human |
Gene Type | protein-coding |
Description | purinergic receptor P2X, ligand gated ion channel, 6 |
Other Description | ATP receptor|P2X purinoceptor 6|purinergic receptor P2X, ligand-gated ion channel, 6|purinergic receptor P2X-like 1, orphan receptor|purinoceptor P2X6|purinoreceptor P2X6|skeletal muscle-expressed P2X |
Swissprots | Q6IC33 Q58F04 Q32MB6 F6V3D7 Q9UL50 O15547 |
Accessions | BAA22047 EAX02910 EAX02911 EAX02912 EAX02913 EAX02914 O15547 AB002058 BAA22046 AF065385 AAF13303 AK309079 BC033488 AAH33488 BC047287 AAH47287 BC063553 BC064805 AAH64805 BC109209 AAI09210 BI753477 CR456535 CAG30421 CU013135 CAK54566 CU013423 CAK54865 DA333742 XM_005261819 XP_005261876 XM_011530498 XP_011528800 XM_011530499 XP_011528801 XM_011530500 XP_011528802 XM_011530501 XP_011528803 XM_011530502 XP_011528804 XR_937950 XR_937952 XR_937953 NM_001159554 NP_001153026 NM_005446 NP_005437 |
Function | Receptor for ATP that acts as a ligand-gated ion channel. {ECO:0000250}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed predominantly in skeletal muscle. |
Top Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
P2X6 CRISPR/Cas9 KO Plasmid (h) - sc-416264 from Santa Cruz Biotechnology
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P2X6 HDR Plasmid (h) - sc-416264-HDR from Santa Cruz Biotechnology
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P2X6 Double Nickase Plasmid (h) - sc-416264-NIC from Santa Cruz Biotechnology
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P2X6 Double Nickase Plasmid (h2) - sc-416264-NIC-2 from Santa Cruz Biotechnology
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P2X6 CRISPR Activation Plasmid (h) - sc-416264-ACT from Santa Cruz Biotechnology
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P2X6 CRISPR Activation Plasmid (h2) - sc-416264-ACT-2 from Santa Cruz Biotechnology
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P2X6 Lentiviral Activation Particles (h) - sc-416264-LAC from Santa Cruz Biotechnology
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P2X6 Lentiviral Activation Particles (h2) - sc-416264-LAC-2 from Santa Cruz Biotechnology
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P2X6 siRNA (h) - sc-42573 from Santa Cruz Biotechnology
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P2X6 shRNA Plasmid (h) - sc-42573-SH from Santa Cruz Biotechnology
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P2X6 shRNA (h) Lentiviral Particles - sc-42573-V from Santa Cruz Biotechnology
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P2X6/P2RX6 RNAi - H00009127-R01 from Novus Biologicals
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MISSION® esiRNA - EHU056971 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16229 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16229 from Sigma-Aldrich
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P2RX6 siRNA (Human) - CRH6034 from Cohesion Biosciences
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shRNA set against Human P2RX6 (NM_005446.3) - SHH369500 from Creative biogene
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shRNA set against Human P2RXL1(NM_005446.3) - SHR085002 from Creative biogene
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P2RX6 shRNA Plasmid (Human) - CHH6034 from Cohesion Biosciences
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P2RX6 miRNA 3'UTR clone - MiUTR1H-07440 from Creative biogene
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P2RX6 miRNA 3'UTR clone - MiUTR3H-09722 from Creative biogene
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