HLA-DMA

Gene Symbol	HLA-DMA
Entrez Gene	3108
Alt Symbol	D6S222E, DMA, HLADM, RING6
Species	Human
Gene Type	protein-coding
Description	major histocompatibility complex, class II, DM alpha
Other Description	HLA class II histocompatibility antigen, DM alpha chain|MHC class II antigen DMA|class II histocompatibility antigen, M alpha chain|really interesting new gene 6 protein
Swissprots	P28067 Q29639 Q29640
Accessions	AAA56993 AAA56994 AHW47929 AHW47946 AHW47963 AHW47980 BAA31432 CAA54169 CAA54170 CAA60781 EAX03658 EAX03659 EAX03660 P28067 AA649861 AK291858 BAF84547 AK298081 BAH12721 AU100342 BC011447 AAH11447 BC026279 AAH26279 CR450324 CAG29320 DQ892839 ABM83765 DQ896086 ABM87085 X62744 CAA44606 NM_006120 NP_006111
Function	Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO. {ECO:0000269|PubMed:16547258, ECO:0000269|PubMed:8849454, ECO:0000269|PubMed:9768757}.
Subcellular Location	Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Localizes to late endocytic compartment. Associates with lysosome membranes.
Top Pathways	Leishmaniasis, HTLV-I infection, Influenza A, Tuberculosis, Herpes simplex infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HLA DM full length protein - ab116751 from Abcam Category Protein Source Wheat germ Species Human

HLA-DMA Antibody Blocking Peptide - LS-E22400 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human HLA DMA Protein - H00003108-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

HLA class II DM alpha / HLA-DMA - H00003108-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

HLA class II DM alpha / HLA-DMA - H00003108-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

HLA-DMA fusion protein - Ag2452 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human HLA-DMA - HLA-DMA-27713TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human HLA-DMA, GST-tagged - HLA-DMA-13812H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant human HLA-DMA protein - CSB-EP338892HU from Cusabio Category Protein Source E.coli Species Human

Recombinant Human HLA class II histocompatibility antigen, DM alpha chain(HLA-D - CSB-YP338892HU CSB-EP338892HU CSB-BP338892HU CSB-MP338892HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

HLA-DMA Protein - abx164028 from Abbexa Category Protein Species Human, Mouse

HLA DMA Recombinant Protein Antigen - NBP1-85325PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

HLA-DMA Peptide, Human - M34GP07087H from Creative Peptides Category Peptide Source Synthetic. Species Human

HLA-DMA Recombinant Protein (OPCA03187) - OPCA03187 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Human HLA-DMA protein - orb358415 from Biorbyt Category Protein Prices $221.00, $366.00, $646.00, $1,071.00, $1,692.00 Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg Species Human

HLA-DMA, Recombinant Protein - MBS1258275 from MyBioSource Category Protein Prices $110.00, $285.00, $460.00, $490.00, $750.00, $755.00, $905.00, $1,015.00, $1,140.00, $1,145.00, $1,145.00, $1,180.00, $1,645.00, $1,740.00, $1,740.00, $2,195.00 Sizes 10 µg (E-Coli), 100 µg (E-Coli), 200 µg (E-Coli), 50 µg (E-Coli), 500 µg (E-Coli), 50 µg (Yeast), 50 µg (Baculovirus), 200 µg (Yeast), 100 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 500 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

HLA-DMA, Recombinant Protein - MBS9423395 from MyBioSource Category Protein Prices $165.00, $280.00, $435.00, $665.00, $1,080.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg Source E Coli Species Human

HLA DMA Recombinant Protein Antigen - NBP2-55086PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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