Gene Symbol | GPR6 |
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Entrez Gene | 2830 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | G protein-coupled receptor 6 |
Other Description | G-protein coupled receptor 6|sphingosine 1-phosphate receptor GPR6 |
Swissprots | Q17RJ7 Q5SYL0 P46095 J3KQR3 B4DHS9 |
Accessions | AAA63181 AAA91631 EAW48331 P46095 AK294648 BAG57824 AK295250 BAG58241 BC043414 AAH43414 BC117298 AAI17299 BC126301 AAI26302 CF147782 DA205492 DA260869 HQ258210 ADR82964 HQ258216 ADR82970 HQ709190 ADZ17397 HQ709191 ADZ17398 NM_001286099 NP_001273028 NM_005284 NP_005275 |
Function | Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000305|PubMed:19059244}; Multi-pass membrane protein {ECO:0000305|PubMed:19059244}. Note=Detected in the intracellular compartments. It is currently unclear whether this is a cell surface or intracellular receptor. |
GPR6 CRISPR/Cas9 KO Plasmid (h) - sc-410801 from Santa Cruz Biotechnology
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GPR6 HDR Plasmid (h) - sc-410801-HDR from Santa Cruz Biotechnology
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GPR6 Double Nickase Plasmid (h) - sc-410801-NIC from Santa Cruz Biotechnology
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GPR6 Double Nickase Plasmid (h2) - sc-410801-NIC-2 from Santa Cruz Biotechnology
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GPR6 CRISPR Activation Plasmid (h) - sc-410801-ACT from Santa Cruz Biotechnology
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GPR6 CRISPR Activation Plasmid (h2) - sc-410801-ACT-2 from Santa Cruz Biotechnology
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GPR6 Lentiviral Activation Particles (h) - sc-410801-LAC from Santa Cruz Biotechnology
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GPR6 Lentiviral Activation Particles (h2) - sc-410801-LAC-2 from Santa Cruz Biotechnology
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GPR6 siRNA (h) - sc-62397 from Santa Cruz Biotechnology
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GPR6 shRNA Plasmid (h) - sc-62397-SH from Santa Cruz Biotechnology
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GPR6 shRNA (h) Lentiviral Particles - sc-62397-V from Santa Cruz Biotechnology
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GPR6 RNAi - H00002830-R02 from Novus Biologicals
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MISSION® esiRNA - EHU032511 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9609 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9609 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04958 from Sigma-Aldrich
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GPR6 siRNA (Human) - CRH1895 from Cohesion Biosciences
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GPR6 - MBS8224982 from MyBioSource
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shRNA set against Human GPR6 (NM_005284.3) - SHH306930 from Creative biogene
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shRNA set against Human GPR6(NM_005284.3) - SHH100467 from Creative biogene
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Human GPR6 siRNA - orb262397 from Biorbyt
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GPR6 shRNA Plasmid (Human) - CHH1895 from Cohesion Biosciences
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GPR6 miRNA 3'UTR clone - MiUTR1H-04220 from Creative biogene
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