Gene Symbol | CDH23 |
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Entrez Gene | 64072 |
Alt Symbol | CDHR23, USH1D |
Species | Human |
Gene Type | protein-coding |
Description | cadherin-related 23 |
Other Description | cadherin-23|cadherin-like 23|cadherin-related family member 23|otocadherin |
Swissprots | Q9H251 Q5QGS2 Q5XKN2 F6U049 C4IXS9 Q5QGS1 Q96JL3 Q9H4K9 Q5QGS5 Q6UWW1 Q5QGS6 |
Accessions | CCQ43681 EAW54426 EAW54427 EAW54428 EAW54429 EAW54430 EAW54431 EAW54432 Q9H251 AB053445 BAB61902 AB058715 BAB47441 AF312024 AAG48303 AK074160 BAB84986 AK093818 BAC04231 AL122081 CAB59256 AY010111 AAG27034 AY358617 AAQ88980 AY563161 AAT72161 AY563162 AAT72162 AY563165 AAT72165 AY563166 AAT72166 BC011570 AAH11570 BC032581 AAH32581 BC065284 AAH65284 BC108254 AAI08255 BC136976 AAI36977 BC136977 AAI36978 BC139903 AAI39904 BM673126 BU728250 DB333699 JF432310 ADZ15527 XM_006717940 XP_006718003 XM_006717942 XP_006718005 XM_011540039 XP_011538341 XM_011540040 XP_011538342 XM_011540041 XP_011538343 XM_011540042 XP_011538344 XM_011540043 XP_011538345 XM_011540044 XP_011538346 XM_011540045 XP_011538347 XM_011540046 XP_011538348 XM_011540047 XP_011538349 XM_011540048 XP_011538350 XM_011540049 XP_011538351 XM_011540050 XP_011538352 XM_011540051 XP_011538353 XM_011540052 XP_011538354 XM_011540053 XP_011538355 XM_011540054 XP_011538356 XR_945796 NM_001171930 NP_001165401 NM_001171931 NP_001165402 NM_001171932 NP_001165403 NM_001171933 NP_001165404 NM_001171934 NP_001165405 NM_001171935 NP_001165406 NM_001171936 NP_001165407 NM_022124 NP_071407 NM_052836 NP_443068 |
Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Particularly strong expression in the retina. Found also in the cochlea. |
Human Cadherin like 23 protein fragment - ab163768 from Abcam
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CDH23 / Cadherin 23 Antibody Blocking Peptide - LS-E17935 from LifeSpan Bioscience
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CDH23 / Cadherin 23 Antibody Blocking Peptide - LS-E26840 from LifeSpan Bioscience
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Recombinant Human Cadherin-23 Protein - H00064072-Q01 from Novus Biologicals
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Recombinant Human Cadherin-23 Protein - H00064072-G01-10ug from Novus Biologicals
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CDH23 blocking peptide - GTX88601-PEP from GeneTex
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CDH23 Blocking Peptide - 33R-2240 from Fitzgerald
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Cadherin like 23 Peptide - AC21-1672-P from Abcore
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Cadherin-23 - H00064072-Q01-10 from Acris Antibodies
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Cadherin-23 - H00064072-Q01-25 from Acris Antibodies
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Cadherin-like 23 Peptide - 46-822P from ProSci
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CDH23 fusion protein - Ag4322 from Proteintech Group
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Recombinant Human CDH23, GST-tagged - CDH23-11038H from Creative Biomart
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Recombinant Cadherin 23 (CDH23) - RPG429Hu01 from Uscn Life Science Inc.
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Cadherin 23 Blocking Peptide - CBP3534 from Cohesion Biosciences
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Recombinant Cadherin 23 (CDH23) - RPG429Hu01 from Cloud-clone
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Recombinant Human Cadherin-23(CDH23) ,partial - CSB-YP872438HU CSB-EP872438HU CSB-BP872438HU CSB-MP872438HU from Cusabio
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Cadherin-23 (transcript variant 2) - TP315133 from Acris Antibodies
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Cadherin 23, Recombinant Protein - MBS2030718 from MyBioSource
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Cadherin-23 (CDH23), partial, Recombinant Protein - MBS1326512 from MyBioSource
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CDH23/USH1D, Peptide - MBS425205 from MyBioSource
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Cadherin-23 Recombinant Protein Antigen - NBP1-85704PEP from Novus Biologicals
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CDH23 Peptide, Human - M34GP02841H from Creative Peptides
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CDH23 Immunizing peptide - orb15481 from Biorbyt
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CDH23 Recombinant Protein (OPCD02069) - OPCD02069 from Aviva Systems Biology
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