Gene Symbol |
Myt1
|
Entrez Gene |
17932
|
Alt Symbol |
Nzf2, Nzf2a, Nzf2b, Nztf2
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
myelin transcription factor 1
|
Other Description |
NZF-2|neural zinc finger factor 2|neural zinc finger transcription factor 2
|
Swissprots |
B0R0C3 B0R0C4 O08995 Q8CFC2 Q8CFH1
|
Accessions |
EDL07461 EDL07462 Q8CFC2 AB082378 BAC16512 AB093267 BAC41451 AF004294 AAC53456 AK082994 AK133358 AK135131 BAE22433 AK165786 BC063252 AAH63252 BM935652 CV559907 XM_006500577 XP_006500640 XM_006500578 XP_006500641 XM_006500579 XP_006500642 XM_006500580 XP_006500643 XM_006500581 XP_006500644 XM_011239932 XP_011238234 XR_375392 NM_001171615 NP_001165086 NM_001171616 NP_001165087 NM_001171680 NP_001165151 NM_008665 NP_032691
|
Function |
Binds to the promoter regions of proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendrogalia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000250}.
|
Tissue Specificity |
Isoform 1 is more predominant than isoform 2 at all stages of development and adulthood. Expressed in differentiated neurons especially at higher levels in newly generated ones. {ECO:0000269|PubMed:12351189}.
|