Gene Symbol | GTPBP10 |
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Entrez Gene | 85865 |
Alt Symbol | ObgH2, UG0751c10 |
Species | Human |
Gene Type | protein-coding |
Description | GTP-binding protein 10 (putative) |
Other Description | GTP-binding protein 10|protein obg homolog 2 |
Swissprots | Q8IXG8 Q3B7A6 Q8WU16 A4D1E9 Q8N982 Q9Y6T6 B4DFY6 Q5H9V2 Q9BSP1 |
Accessions | A4D1E9 AAD15550 EAL24164 EAW76878 EAW76879 EAW76880 EAW76881 EAW76882 AF351613 AAN76513 AK093649 AK095561 BAC04573 AK125553 AK294325 BAG57597 AL525056 BC004923 AAH04923 BC021573 AAH21573 BC107714 AAI07715 BC144162 CR933597 CAI45922 T65158 NM_001042717 NP_001036182 NM_033107 NP_149098 |
Function | May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nuceleolar architecture is observed. {ECO:0000269|PubMed:17054726}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:17054726}. Chromosome {ECO:0000269|PubMed:17054726}. Note=Found in the dense fibrillar compartment region of the nucleolus. At the onset of mitosis moves to the chromosome surface and remains there until anaphase. Gradually re-assembles into the nucleolus at late anaphase to telophase. |
GTPBP10 CRISPR/Cas9 KO Plasmid (h) - sc-413794 from Santa Cruz Biotechnology
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GTPBP10 HDR Plasmid (h) - sc-413794-HDR from Santa Cruz Biotechnology
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GTPBP10 Double Nickase Plasmid (h) - sc-413794-NIC from Santa Cruz Biotechnology
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GTPBP10 Double Nickase Plasmid (h2) - sc-413794-NIC-2 from Santa Cruz Biotechnology
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GTPBP10 CRISPR Activation Plasmid (h) - sc-413794-ACT from Santa Cruz Biotechnology
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GTPBP10 CRISPR Activation Plasmid (h2) - sc-413794-ACT-2 from Santa Cruz Biotechnology
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GTPBP10 Lentiviral Activation Particles (h) - sc-413794-LAC from Santa Cruz Biotechnology
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GTPBP10 Lentiviral Activation Particles (h2) - sc-413794-LAC-2 from Santa Cruz Biotechnology
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GTPBP10 siRNA (h) - sc-89367 from Santa Cruz Biotechnology
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GTPBP10 shRNA Plasmid (h) - sc-89367-SH from Santa Cruz Biotechnology
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GTPBP10 shRNA (h) Lentiviral Particles - sc-89367-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU072601 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9783 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9783 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11144 from Sigma-Aldrich
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GTPBP10 siRNA (Human) - CRJ3842 from Cohesion Biosciences
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GTPBP10 - MBS8236743 from MyBioSource
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shRNA set against Human GTPBP10 (NM_033107.3) - SHH309138 from Creative biogene
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GTPBP10 CRISPR/Cas9 KO Plasmid (h2) - sc-413794-KO-2 from Santa Cruz Biotechnology
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GTPBP10 HDR Plasmid (h2) - sc-413794-HDR-2 from Santa Cruz Biotechnology
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GTPBP10 shRNA Plasmid (Human) - CHJ3842 from Cohesion Biosciences
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