Gene Symbol | BRD2 |
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Entrez Gene | 6046 |
Alt Symbol | D6S113E, FSH, FSRG1, NAT, RING3, RNF3 |
Species | Human |
Gene Type | protein-coding |
Description | bromodomain containing 2 |
Other Description | O27.1.1|bromodomain-containing 2|bromodomain-containing protein 2|female sterile homeotic-related gene 1|really interesting new gene 3 protein |
Swissprots | B0S7P0 P25440 Q63HQ9 O00699 A2AAU0 Q658Y7 B1AZT1 O00700 Q969U4 Q6P3U2 Q15310 Q5STC9 |
Accessions | AAD24963 AHW47930 AHW47947 AHW47964 AHW47981 CAA65450 CAC69989 EAX03662 EAX03663 EAX03664 EAX03665 EAX03666 P25440 AI983495 AK056504 AK309797 AL832722 CAH56208 AY152720 BC000477 BC001885 BC007715 BC063840 AAH63840 BP271262 BX647233 CAH56179 BX648109 CAH56171 CN398334 D42040 BAA07641 DA127395 DA505721 DC379337 H11588 HY065625 M80613 AAA68890 S78771 X62083 CAA43996 XR_241911 XR_246967 XR_247375 XR_247406 XR_247427 XR_926296 XR_952210 XR_952834 XR_953008 XR_953082 NM_001113182 NP_001106653 NM_001199455 NP_001186384 NM_001199456 NP_001186385 NM_005104 NP_005095 NR_037625 NM_001291986 NP_001278915 |
Function | May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. {ECO:0000250, ECO:0000269|PubMed:18406326}. |
Subcellular Location | Nucleus {ECO:0000305}. Note=Detected on chromatin and nucleosomes. |
BRD2 CRISPR/Cas9 KO Plasmid (h) - sc-402584 from Santa Cruz Biotechnology
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BRD2 HDR Plasmid (h) - sc-402584-HDR from Santa Cruz Biotechnology
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BRD2 Double Nickase Plasmid (h) - sc-402584-NIC from Santa Cruz Biotechnology
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BRD2 Double Nickase Plasmid (h2) - sc-402584-NIC-2 from Santa Cruz Biotechnology
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BRD2 CRISPR Activation Plasmid (h) - sc-402584-ACT from Santa Cruz Biotechnology
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BRD2 CRISPR Activation Plasmid (h2) - sc-402584-ACT-2 from Santa Cruz Biotechnology
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BRD2 Lentiviral Activation Particles (h) - sc-402584-LAC from Santa Cruz Biotechnology
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BRD2 Lentiviral Activation Particles (h2) - sc-402584-LAC-2 from Santa Cruz Biotechnology
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BRD2 siRNA (h) - sc-60282 from Santa Cruz Biotechnology
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BRD2 shRNA Plasmid (h) - sc-60282-SH from Santa Cruz Biotechnology
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BRD2 shRNA (h) Lentiviral Particles - sc-60282-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU108021 from Sigma-Aldrich
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MISSION® siRNA - SIHK0188 from Sigma-Aldrich
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MISSION® siRNA - SIHK0187 from Sigma-Aldrich
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MISSION® siRNA - SIHK0185 from Sigma-Aldrich
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MISSION® siRNA - SIHK0186 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4048 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4048 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04635 from Sigma-Aldrich
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BRD2 siRNA (Human) - CRH4093 from Cohesion Biosciences
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BRD2 RNAi - H00006046-R02 from Novus Biologicals
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BRD2 - MBS827296 from MyBioSource
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shRNA set against Human BRD2 (NM_005104.3) - SHH247594 from Creative biogene
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shRNA set against Human BRD2(NM_005104.3) - SHG104131 from Creative biogene
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Human BRD2 siRNA - orb264595 from Biorbyt
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