Gene Symbol | GLRA2 |
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Entrez Gene | 2742 |
Alt Symbol | GLR |
Species | Human |
Gene Type | protein-coding |
Description | glycine receptor, alpha 2 |
Other Description | glycine receptor alpha 2 subunit|glycine receptor subunit alpha-2|glycine receptor, alpha-2 polypeptide |
Swissprots | B7Z4F5 B2R6I8 A8K0J6 Q53YX7 Q6ICQ0 Q99862 P23416 J3KQ59 |
Accessions | AAB38272 AAB38273 AAC35290 EAW98858 EAW98859 EAW98860 P23416 AA081959 AK289561 BAF82250 AK297268 BAH12535 AK297304 BAH12541 AK312591 BAG35485 AY437083 AAR87842 AY437084 AAR87843 BC032864 AAH32864 BC045547 CR450343 CAG29339 DA495302 HQ448005 ADQ32486 X52008 CAA36257 XM_006724487 XP_006724550 XM_011545495 XP_011543797 XM_011545496 XP_011543798 NM_001118885 NP_001112357 NM_001118886 NP_001112358 NM_001171942 NP_001165413 NM_002063 NP_002054 |
Function | The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | Neuroactive ligand-receptor interaction |
GlyR α2 CRISPR/Cas9 KO Plasmid (h) - sc-402179 from Santa Cruz Biotechnology
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GlyR α2 HDR Plasmid (h) - sc-402179-HDR from Santa Cruz Biotechnology
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GlyR α2 Double Nickase Plasmid (h) - sc-402179-NIC from Santa Cruz Biotechnology
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GlyR α2 Double Nickase Plasmid (h2) - sc-402179-NIC-2 from Santa Cruz Biotechnology
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GlyR α2 CRISPR Activation Plasmid (h) - sc-402179-ACT from Santa Cruz Biotechnology
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GlyR α2 CRISPR Activation Plasmid (h2) - sc-402179-ACT-2 from Santa Cruz Biotechnology
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GlyR α2 Lentiviral Activation Particles (h) - sc-402179-LAC from Santa Cruz Biotechnology
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GlyR α2 Lentiviral Activation Particles (h2) - sc-402179-LAC-2 from Santa Cruz Biotechnology
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GlyR α2 siRNA (h) - sc-35499 from Santa Cruz Biotechnology
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GlyR α2 shRNA Plasmid (h) - sc-35499-SH from Santa Cruz Biotechnology
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GlyR α2 shRNA (h) Lentiviral Particles - sc-35499-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU061551 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2045 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2045 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08852 from Sigma-Aldrich
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GLRA2 siRNA (Human) - CRH1826 from Cohesion Biosciences
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Glycine Receptor alpha 1 + alpha 2 RNAi - H00002742-R01 from Novus Biologicals
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GLRA2 - MBS8235992 from MyBioSource
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shRNA set against Human GLRA2 (NM_002063.3) - SHH301938 from Creative biogene
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Human GLRA2 siRNA - orb262328 from Biorbyt
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GLRA2 shRNA Plasmid (Human) - CHH1826 from Cohesion Biosciences
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GLRA2 miRNA 3'UTR clone - MiUTR3H-02974 from Creative biogene
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GLRA2 miRNA 3'UTR clone - MiUTR3H-02975 from Creative biogene
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GLRA2 miRNA 3'UTR clone - MiUTR3H-02976 from Creative biogene
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