Gene Symbol | PTCD1 |
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Entrez Gene | 26024 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | pentatricopeptide repeat domain 1 |
Other Description | pentatricopeptide repeat-containing protein 1, mitochondrial |
Swissprots | Q66K60 Q9UDV2 O75127 Q3ZB78 |
Accessions | EAL23880 EAW76669 O75127 AB014532 BAA31607 AB073644 AK001615 BAG50949 AK291004 BAF83693 AK307981 BC003688 AAH03688 BC024042 BC080580 AAH80580 BC103495 AAI03496 BC103502 AAI03503 BC103661 AAI03662 BG717613 DA770648 NM_015545 NP_056360 |
Function | Mitochondrial protein implicated in negative regulation of leucine tRNA levels, as well as negative regulation of mitochondria-encoded proteins and COX activity. Affects also the 3'-processing of mitochondrial tRNAs. {ECO:0000269|PubMed:21857155}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:19651879, ECO:0000269|PubMed:21857155}. Mitochondrion matrix {ECO:0000250}. |
Tissue Specificity | Abundant in testes, skeletal muscle and heart. {ECO:0000269|PubMed:19651879}. |
PTCD1 CRISPR/Cas9 KO Plasmid (h) - sc-408214 from Santa Cruz Biotechnology
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PTCD1 HDR Plasmid (h) - sc-408214-HDR from Santa Cruz Biotechnology
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PTCD1 Double Nickase Plasmid (h) - sc-408214-NIC from Santa Cruz Biotechnology
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PTCD1 Double Nickase Plasmid (h2) - sc-408214-NIC-2 from Santa Cruz Biotechnology
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PTCD1 CRISPR Activation Plasmid (h) - sc-408214-ACT from Santa Cruz Biotechnology
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PTCD1 CRISPR Activation Plasmid (h2) - sc-408214-ACT-2 from Santa Cruz Biotechnology
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PTCD1 Lentiviral Activation Particles (h) - sc-408214-LAC from Santa Cruz Biotechnology
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PTCD1 Lentiviral Activation Particles (h2) - sc-408214-LAC-2 from Santa Cruz Biotechnology
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PTCD1 siRNA (h) - sc-89388 from Santa Cruz Biotechnology
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PTCD1 shRNA Plasmid (h) - sc-89388-SH from Santa Cruz Biotechnology
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PTCD1 shRNA (h) Lentiviral Particles - sc-89388-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU001011 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17651 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17651 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12393 from Sigma-Aldrich
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PTCD1 siRNA (Human) - CRH8660 from Cohesion Biosciences
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shRNA set against Human PTCD1 (NM_015545.3) - SHH385784 from Creative biogene
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Human PTCD1 siRNA - orb269162 from Biorbyt
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PTCD1 shRNA Plasmid (Human) - CHH8660 from Cohesion Biosciences
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PTCD1 miRNA 3'UTR clone - MiUTR3H-13395 from Creative biogene
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