Gene Symbol | UQCRFS1 |
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Entrez Gene | 7386 |
Alt Symbol | RIP1, RIS1, RISP, UQCR5 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 |
Other Description | Rieske iron-sulfur protein|complex III subunit 5|cytochrome b-c1 complex subunit 5|cytochrome b-c1 complex subunit Rieske, mitochondrial|ubiquinol-cytochrome c reductase iron-sulfur subunit |
Swissprots | Q6NVX5 P47985 Q9UPH2 A8K519 |
Accessions | AAC41754 AAD38242 P47985 AK000225 AK291134 BAF83823 BC000649 AAH00649 BC010035 AAH10035 BC067832 AAH67832 BF210184 BF979273 DQ891841 ABM82767 HQ447986 ADQ32468 NM_006003 NP_005994 |
Function | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. |
Subcellular Location | Mitochondrion inner membrane; Single-pass membrane protein. |
Top Pathways | Alzheimer's disease, Huntington's disease, Cardiac muscle contraction, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
Rieske FeS CRISPR/Cas9 KO Plasmid (h) - sc-403504 from Santa Cruz Biotechnology
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Rieske FeS HDR Plasmid (h) - sc-403504-HDR from Santa Cruz Biotechnology
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Rieske FeS Double Nickase Plasmid (h) - sc-403504-NIC from Santa Cruz Biotechnology
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Rieske FeS Double Nickase Plasmid (h2) - sc-403504-NIC-2 from Santa Cruz Biotechnology
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Rieske FeS CRISPR Activation Plasmid (h) - sc-403504-ACT from Santa Cruz Biotechnology
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Rieske FeS CRISPR Activation Plasmid (h2) - sc-403504-ACT-2 from Santa Cruz Biotechnology
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Rieske FeS Lentiviral Activation Particles (h) - sc-403504-LAC from Santa Cruz Biotechnology
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Rieske FeS Lentiviral Activation Particles (h2) - sc-403504-LAC-2 from Santa Cruz Biotechnology
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Rieske FeS siRNA (h) - sc-72148 from Santa Cruz Biotechnology
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Rieske FeS shRNA Plasmid (h) - sc-72148-SH from Santa Cruz Biotechnology
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Rieske FeS shRNA (h) Lentiviral Particles - sc-72148-V from Santa Cruz Biotechnology
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UQCRFS1 RNAi - H00007386-R01 from Novus Biologicals
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MISSION® esiRNA - EHU106991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22535 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22535 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02375 from Sigma-Aldrich
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UQCRFS1 siRNA (Human) - CRH5053 from Cohesion Biosciences
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UQCRFS1 - MBS8220729 from MyBioSource
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shRNA set against Human Uqcrfs1 (NM_006003.2) - SHH440960 from Creative biogene
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shRNA set against Human UQCRFS1(NM_006003.2) - SHL116086 from Creative biogene
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Human UQCRFS1 siRNA - orb265555 from Biorbyt
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UQCRFS1 shRNA Plasmid (Human) - CHH5053 from Cohesion Biosciences
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UQCRFS1 miRNA 3'UTR clone - MiUTR1H-11033 from Creative biogene
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