Gene Symbol | SLC6A11 |
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Entrez Gene | 6538 |
Alt Symbol | GAT-3, GAT3, GAT4 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 6 (neurotransmitter transporter), member 11 |
Other Description | GABA transporter 3|sodium- and chloride-dependent GABA transporter 3|solute carrier family 6 (neurotransmitter transporter, GABA), member 11|solute carrier family 6 member 11 |
Swissprots | B2R6U6 Q8IYC9 P48066 |
Accessions | CAL40956 EAW64086 EAW64087 P48066 AK312719 BAG35593 BC036083 AAH36083 BC152735 AAI52736 S75989 AAB33570 XM_011534032 XP_011532334 XM_011534033 XP_011532335 NM_014229 NP_055044 |
Function | Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Widespread distribution in the brain. |
Top Pathways | GABAergic synapse |
GABA T-3 CRISPR/Cas9 KO Plasmid (h) - sc-403545 from Santa Cruz Biotechnology
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GABA T-3 HDR Plasmid (h) - sc-403545-HDR from Santa Cruz Biotechnology
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GABA T-3 Double Nickase Plasmid (h) - sc-403545-NIC from Santa Cruz Biotechnology
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GABA T-3 Double Nickase Plasmid (h2) - sc-403545-NIC-2 from Santa Cruz Biotechnology
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GABA T-3 CRISPR Activation Plasmid (h) - sc-403545-ACT from Santa Cruz Biotechnology
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GABA T-3 CRISPR Activation Plasmid (h2) - sc-403545-ACT-2 from Santa Cruz Biotechnology
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GABA T-3 Lentiviral Activation Particles (h) - sc-403545-LAC from Santa Cruz Biotechnology
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GABA T-3 Lentiviral Activation Particles (h2) - sc-403545-LAC-2 from Santa Cruz Biotechnology
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GABA T-3 siRNA (h) - sc-41962 from Santa Cruz Biotechnology
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GABA T-3 shRNA Plasmid (h) - sc-41962-SH from Santa Cruz Biotechnology
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GABA T-3 shRNA (h) Lentiviral Particles - sc-41962-V from Santa Cruz Biotechnology
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GAT3 RNAi - H00006538-R01 from Novus Biologicals
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MISSION® esiRNA - EHU062501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19672 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19672 from Sigma-Aldrich
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SLC6A11 siRNA (Human) - CRH4431 from Cohesion Biosciences
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SLC6A11 - MBS829785 from MyBioSource
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GABA T-3 CRISPR/Cas9 KO Plasmid (h2) - sc-403545-KO-2 from Santa Cruz Biotechnology
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GABA T-3 HDR Plasmid (h2) - sc-403545-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human SLC6A11 (NM_014229.1) - SHH411812 from Creative biogene
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shRNA set against Human SLC6A11(NM_014229.1) - SHL010810 from Creative biogene
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SLC6A11 shRNA Plasmid (Human) - CHH4431 from Cohesion Biosciences
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SLC6A11 miRNA 3'UTR clone - MiUTR1H-09590 from Creative biogene
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