Gene Symbol | SLC1A4 |
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Entrez Gene | 6509 |
Alt Symbol | ASCT1, SATT |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
Other Description | ASCT-1|alanine/serine/cysteine/threonine transporter 1|glutamate/neutral amino acid transporter|neutral amino acid transporter A|solute carrier family 1 member 4 |
Swissprots | D6W5F0 P43007 B7Z3C0 |
Accessions | AAC51349 AAF03519 EAW99932 EAW99933 P43007 AB026689 BAA94861 AK126636 AK223486 BAD97206 AK295687 BAH12156 AK298472 BAH12797 AK313052 BAG35883 AK315986 BAH14357 BC007350 BC026216 AAH26216 BC072423 AAH72423 BI553783 CR990382 DA214889 DA218921 DQ891127 ABM82053 DQ894306 ABM85232 L14595 AAA02761 L19444 AAA19438 XM_006712079 XP_006712142 NM_001135581 NM_001193493 NP_001180422 NM_003038 NP_003029 |
Function | Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence. |
Subcellular Location | Membrane {ECO:0000269|PubMed:17081065}; Multi-pass membrane protein {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Tissue Specificity | Expressed mostly in brain, muscle, and pancreas but detected in all tissues examined. |
ASCT1 CRISPR/Cas9 KO Plasmid (h) - sc-409194 from Santa Cruz Biotechnology
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ASCT1 HDR Plasmid (h) - sc-409194-HDR from Santa Cruz Biotechnology
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ASCT1 Double Nickase Plasmid (h) - sc-409194-NIC from Santa Cruz Biotechnology
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ASCT1 Double Nickase Plasmid (h2) - sc-409194-NIC-2 from Santa Cruz Biotechnology
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ASCT1 CRISPR Activation Plasmid (h) - sc-409194-ACT from Santa Cruz Biotechnology
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ASCT1 CRISPR Activation Plasmid (h2) - sc-409194-ACT-2 from Santa Cruz Biotechnology
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ASCT1 Lentiviral Activation Particles (h) - sc-409194-LAC from Santa Cruz Biotechnology
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ASCT1 Lentiviral Activation Particles (h2) - sc-409194-LAC-2 from Santa Cruz Biotechnology
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ASCT1 siRNA (h) - sc-60208 from Santa Cruz Biotechnology
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ASCT1 shRNA Plasmid (h) - sc-60208-SH from Santa Cruz Biotechnology
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ASCT1 shRNA (h) Lentiviral Particles - sc-60208-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU019321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19448 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19448 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12949 from Sigma-Aldrich
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SLC1A4 siRNA (Human) - CRH4404 from Cohesion Biosciences
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SLC1A4 RNAi - H00006509-R01 from Novus Biologicals
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SLC1A4 - MBS8218893 from MyBioSource
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shRNA set against Human SLC1A4 (NM_003038.4) - SHH408932 from Creative biogene
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SLC1A4 shRNA Plasmid (Human) - CHH4404 from Cohesion Biosciences
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SLC1A4 miRNA 3'UTR clone - MiUTR4H-TG08102 from Creative biogene
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