Gene Symbol | POR |
---|---|
Entrez Gene | 5447 |
Alt Symbol | CPR, CYPOR, P450R |
Species | Human |
Gene Type | protein-coding |
Description | P450 (cytochrome) oxidoreductase |
Other Description | NADPH--cytochrome P450 reductase|NADPH-dependent cytochrome P450 reductase |
Swissprots | Q8N181 P16435 Q197M5 Q16455 Q9UDT3 Q9H3M8 |
Accessions | AAD45961 ABF70199 EAW71777 EAW71778 EAW71779 EAW71780 P16435 AB051763 BAB18572 AB209874 BAD93111 AF258341 AAG09798 AK129978 AK290529 BAF83218 AK293194 BAG56734 AK296096 BAG58850 AK296639 BAG59240 AK304511 BAG65317 AK312543 BAG35442 BC034277 AAH34277 BG104767 BP244929 BX648619 CAH56151 DA701694 S90469 AAB21814 NM_000941 NP_000932 |
Function | This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. |
Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Anchored to the ER membrane by its N- terminal hydrophobic region. |