| Gene Symbol |
SLC13A3
|
| Entrez Gene |
64849
|
| Alt Symbol |
NADC3, SDCT2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
|
| Other Description |
Na(+)/dicarboxylate cotransporter 3|hNaDC3|naDC-3|sodium-dependent high affinity dicarboxylate transporter 3|sodium-dependent high-affinity dicarboxylate transporter 2|solute carrier family 13 member 3
|
| Swissprots |
Q9NS04 Q5TCQ2 Q9NQN5 Q9H3W4 Q96MM5 F6WI18 Q9BR25 Q8WWT9 Q5JYD0 Q8IVB1 Q9H1G1 Q5JYC9 E1P5U4 Q8N8K4 Q5JYD1 B4DIR8
|
| Accessions |
EAW75725 EAW75726 Q8WWT9 AF154121 AAF73251 AK023307 AK056713 BAB71262 AK096658 BAC04834 AK123351 AK293902 BAG57288 AK295748 BAG58580 AK303709 BAG64693 AK310767 AK310960 AK315131 AL442082 CAC09447 AY072810 AAL66762 BC014931 BC035966 AAH35966 BM474324 BP358260 BQ946167 CB997336 CN310376 DA272524 DA334816 DA503319 DA636764 DQ892655 ABM83581 DQ895894 ABM86820 NM_001011554 NP_001011554 NM_001193339 NP_001180268 NM_001193340 NP_001180269 NM_001193342 NP_001180271 NM_022829 NP_073740
|
| Function |
High-affinity sodium-dicarboxylate cotransporter that accepts a range of substrates with 4-5 carbon atoms. The stoichiometry is probably 3 Na(+) for 1 divalent succinate.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:17426067}; Multi-pass membrane protein {ECO:0000269|PubMed:17426067}.
|
| Tissue Specificity |
Expression is highest in kidney. Detected in placenta, brain, liver and pancreas.
|