Gene Symbol | CYB5R1 |
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Entrez Gene | 51706 |
Alt Symbol | B5R.1, B5R1, B5R2, NQO3A2, humb5R2 |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome b5 reductase 1 |
Other Description | NAD(P)H:quinone oxidoreductase type 3, polypeptide A2|NADH-cytochrome b5 reductase 1 |
Swissprots | O95329 Q9UHQ9 Q53F73 B2R8E0 Q8NCL5 A0PK21 Q9UHJ1 |
Accessions | CAF86916 CAI93434 EAW91451 EAW91452 EAW91453 EAW91454 Q9UHQ9 AF087912 AAP97209 AF091084 AAC72953 AF093822 AAP97218 AF125533 AAF17227 AF169481 AAF06147 AK074654 BAC11115 AK075304 AK123705 AK223416 BAD97136 AK295902 BAG58694 AK313333 BAG36137 AY359026 AAQ89385 BC000034 BC018732 AAH18732 BC127945 AAI27946 HQ447176 ADQ31663 NM_016243 NP_057327 |
Function | NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:10611283}. |
Top Pathways | Amino sugar and nucleotide sugar metabolism |
CYB5R1 CRISPR/Cas9 KO Plasmid (h) - sc-409272 from Santa Cruz Biotechnology
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CYB5R1 HDR Plasmid (h) - sc-409272-HDR from Santa Cruz Biotechnology
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CYB5R1 Double Nickase Plasmid (h) - sc-409272-NIC from Santa Cruz Biotechnology
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CYB5R1 Double Nickase Plasmid (h2) - sc-409272-NIC-2 from Santa Cruz Biotechnology
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CYB5R1 CRISPR Activation Plasmid (h) - sc-409272-ACT from Santa Cruz Biotechnology
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CYB5R1 CRISPR Activation Plasmid (h2) - sc-409272-ACT-2 from Santa Cruz Biotechnology
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CYB5R1 Lentiviral Activation Particles (h) - sc-409272-LAC from Santa Cruz Biotechnology
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CYB5R1 Lentiviral Activation Particles (h2) - sc-409272-LAC-2 from Santa Cruz Biotechnology
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CYB5R1 siRNA (h) - sc-78803 from Santa Cruz Biotechnology
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CYB5R1 shRNA Plasmid (h) - sc-78803-SH from Santa Cruz Biotechnology
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CYB5R1 shRNA (h) Lentiviral Particles - sc-78803-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU154761 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6850 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6850 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05522 from Sigma-Aldrich
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CYB5R1 siRNA (Human) - CRH9912 from Cohesion Biosciences
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CYB5R1 - MBS8230995 from MyBioSource
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shRNA set against Human CYB5R1 (NM_016243.2) - SHH272581 from Creative biogene
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shRNA set against Human CYB5R1(NM_016243.2) - SHG214333 from Creative biogene
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CYB5R1 shRNA Plasmid (Human) - CHH9912 from Cohesion Biosciences
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CYB5R1 miRNA 3'UTR clone - MiUTR1H-02594 from Creative biogene
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