Gene Symbol | KIR2DL4 |
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Entrez Gene | 3805 |
Alt Symbol | CD158D, G9P, KIR-103AS, KIR103, KIR103AS |
Species | Human |
Gene Type | protein-coding |
Description | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 |
Other Description | CD158 antigen-like family member D|MHC class I NK cell receptor KIR103AS|NK cell receptor|killer Ig receptor|killer cell immunoglobulin-like receptor 2DL4|killer cell inhibitory receptor 103AS|natural killer cell inhibitory receptor |
Swissprots | Q99561 Q99560 Q99559 P78401 Q8N738 O14624 P78400 Q9UQJ7 O14623 Q99706 O43534 Q99562 O14622 A8W795 O14621 |
Accessions | AAB61926 AAD24763 AAG01681 AAW32088 AAW32089 AAW32090 AAW32091 AAW32092 AAW32093 AAW32094 AAW32095 ABD38576 ABD38577 ABL09829 ABL14263 ABN13877 ABO14698 ABO14699 ACP20193 ACP20194 ACP20195 ACP20196 ACP20197 ACP20198 ACP20199 ACP20200 ACP20201 ACP20202 ACP20203 ACP20204 ACR40404 ADJ94534 ADJ94550 ADJ94574 ADM52321 ADM52322 ADM64610 ADM64611 ADM64612 ADM64613 ADY38408 ADY38409 ADY38410 ADY38411 ADY38412 ADY38413 ADY38414 ADY38415 ADY90046 ADY90047 ADY90048 AFQ98423 AFQ98424 AFQ98425 AFQ98426 AFQ98427 AFQ98428 AIF79770 AJI80981 AJI80990 AJI80996 AJI81005 AJI81020 AJI81031 AJI81037 AJI81044 CAK18998 CAL49524 CAL49525 CCQ43980 EAW72279 EAW72280 EAW72281 EAW72282 EAW72283 Q99706 AF002256 AAB61282 AF002979 AAB71387 AF002980 AAB71388 AF002981 AAB71389 AF002982 AAB71390 AF034771 AAB95164 AF034772 AAB95165 AF034773 AAB95166 AF276292 AAG44820 AF285436 AAG34927 AK309531 AK310066 AY052496 AAL14211 AY052497 AAL14212 AY052498 AAL14213 AY223512 AAO46034 AY223513 AAO46035 AY223514 AAO46036 AY223515 AAO46037 AY250088 AAP02958 AY359817 AAQ83723 AY601812 AAT11793 AY789058 AAX23103 AY789059 AAX23104 AY789060 AAX23105 AY789061 AAX23106 AY789062 AAX23107 BC028137 BC041611 AAH41611 BM918119 DA590865 DA934665 DQ266438 ABB73033 DQ272466 ABB84493 EU194340 ABW73959 EU194341 ABW73960 EU194342 ABW73961 HQ448395 ADQ32875 U71199 AAB49756 U73394 AAC51146 X97229 CAA65868 X99479 CAA67842 X99480 CAA67843 X99481 CAA67844 Y13054 CAA73497 NM_001080770 NP_001074239 NM_001080772 NP_001074241 NM_002255 NP_002246 NM_001258383 |
Function | Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Top Pathways | Natural killer cell mediated cytotoxicity, Antigen processing and presentation |
KIR2DL4 CRISPR/Cas9 KO Plasmid (h) - sc-416656 from Santa Cruz Biotechnology
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KIR2DL4 HDR Plasmid (h) - sc-416656-HDR from Santa Cruz Biotechnology
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KIR2DL4 Double Nickase Plasmid (h) - sc-416656-NIC from Santa Cruz Biotechnology
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KIR2DL4 Double Nickase Plasmid (h2) - sc-416656-NIC-2 from Santa Cruz Biotechnology
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KIR2DL4 CRISPR Activation Plasmid (h) - sc-416656-ACT from Santa Cruz Biotechnology
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KIR2DL4 CRISPR Activation Plasmid (h2) - sc-416656-ACT-2 from Santa Cruz Biotechnology
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KIR2DL4 Lentiviral Activation Particles (h) - sc-416656-LAC from Santa Cruz Biotechnology
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KIR2DL4 Lentiviral Activation Particles (h2) - sc-416656-LAC-2 from Santa Cruz Biotechnology
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KIR2DL4 siRNA (h) - sc-106765 from Santa Cruz Biotechnology
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KIR2DL4 shRNA Plasmid (h) - sc-106765-SH from Santa Cruz Biotechnology
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KIR2DL4 shRNA (h) Lentiviral Particles - sc-106765-V from Santa Cruz Biotechnology
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KIR2DL4/CD158d RNAi - H00003805-R02 from Novus Biologicals
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MISSION® esiRNA - EHU116531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11219 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11219 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03279 from Sigma-Aldrich
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KIR2DL4 siRNA (Human) - CRH2576 from Cohesion Biosciences
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shRNA set against Human KIR2DL4 (NM_002255.5) - SHH325491 from Creative biogene
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shRNA set against Human KIR2DL4(NM_001080772.1) - SHL197974 from Creative biogene
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shRNA set against Human KIR2DL4(NM_001080770.1) - SHL198018 from Creative biogene
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shRNA set against Human KIR2DL4(NM_002255.5) - SHL198029 from Creative biogene
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shRNA set against Human KIR2DL4(NM_001080770.1) - SHL198030 from Creative biogene
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shRNA set against Human KIR2DL4(NM_002255.5) - SHL198031 from Creative biogene
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shRNA set against Human KIR2DL4(NM_001080770.1) - SHL198032 from Creative biogene
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shRNA set against Human KIR2DL4(NM_002255.5) - SHL198033 from Creative biogene
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