Gene Symbol |
ADGRE3
|
Entrez Gene |
84658
|
Alt Symbol |
EMR3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
adhesion G protein-coupled receptor E3
|
Other Description |
EGF-like module receptor 3|EGF-like module-containing mucin-like hormone receptor-like 3|egf-like module containing, mucin-like, hormone receptor-like 3|egf-like module-containing mucin-like receptor 3
|
Swissprots |
Q9BY15
|
Accessions |
EAW84438 EAW84439 EAW84440 Q9BY15 AF239764 AAK15076 AK290909 BAF83598 AK298653 BAH12837 AL832663 AW450761 AY358817 AAQ89176 BC121130 AAI21131 BC121131 AAI21132 BC128053 AAI28054 BC142639 BC148282 AAI48283 BC166661 AAI66661 XM_005260118 XP_005260175 XM_011528374 XP_011526676 NM_001289158 NP_001276087 NM_001289159 NP_001276088 NM_032571 NP_115960 NM_152939
|
Function |
Receptor probably involved in myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of momocytes- derived macrophages and activated neutrophils.
|
Subcellular Location |
EGF-like module-containing mucin-like hormone receptor-like 3 subunit alpha: Secreted, extracellular space. Note=A soluble form is also detected (alpha subunit).
|
Tissue Specificity |
Displays a predominantly leukocyte-restricted expression, with highest levels in neutrophils, monocytes and macrophages.
|