PDE1A

Gene Symbol PDE1A
Entrez Gene 5136
Alt Symbol CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A
Species Human
Gene Type protein-coding
Description phosphodiesterase 1A, calmodulin-dependent
Other Description 61 kDa Cam-PDE|calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A|calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase|cam-PDE 1A
Swissprots Q9C0L1 Q9C0L2 Q86VZ0 P54750 Q9C0L0 Q9C0K9 Q9UFX3 Q9C0K8 Q9C0L4 Q9C0L3 D3DPG5
Accessions AAD40741 AAY14812 AAY14837 BAB20049 BAB20050 BAB20051 BAB20052 BAB20053 BAB20054 BAB20055 BAB20056 BAB20057 EAX10965 EAX10966 EAX10967 EAX10968 EAX10969 EAX10970 EAX10971 EAX10972 EAX10973 EAX10974 EAX10975 P54750 AA846454 AB038227 BAB20037 AB038228 BAB20038 AF110235 AAD40737 AF110236 AAD40738 AF110237 AAD40739 AF110238 AAD40740 AF110240 AJ401610 CAC82208 AK130643 AK294239 BAH11712 AK295657 BAH12143 AK301720 BAH13538 AL110263 CAB53703 AL536937 BC022480 AAH22480 BC047057 BG196993 BM719913 DA128734 DA295167 DB128091 DB512285 DC396228 DQ892369 ABM83295 DQ893372 ABM84298 DQ895578 ABM86504 DQ896694 ABM87693 U40370 AAC50436 XM_011511323 XP_011509625 XM_011511324 XP_011509626 XM_011511325 XP_011509627 XM_011511326 XP_011509628 XR_922940 NM_001003683 NP_001003683 NM_001258312 NP_001245241 NM_001258313 NP_001245242 NM_001258314 NP_001245243 NM_005019 NP_005010
Function Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.
Tissue Specificity Several tissues, including brain, kidney, testes and heart.
Top Pathways Taste transduction, Calcium signaling pathway, Morphine addiction, Purine metabolism

PDE1A (B-10) - sc-374602 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PDE1A (B-10): sc-374602. Western blot analysis of PDE1A expression in HeLa whole cell lysate.

PDE1A (H-105) - sc-50480 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PDE1A (H-105): sc-50480. Western blot analysis of PDE1A expression in NIH/3T3 whole cell lysate.

PDE1A (Q-13) - sc-67734 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PDE1A (Q-13): sc-67734. Western blot analysis of PDE1A expression in NIH/3T3 (A) and C2C12 (B) whole cell lysates.

Anti-PDE1A antibody - ab14599 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PDE1A Antibody (C-Terminus) - LS-C82364 from LifeSpan Bioscience

Prices $380.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-PDE1A Antibody (aa259-545, clone 5C9) - LS-C338659 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5C9
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDE1A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDE1A.

Anti-PDE1A Antibody (aa51-100) - LS-C81745 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-PDE1A Antibody (C-Terminus) - LS-C135298 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
PDE1A antibody LS-C135298 Western blot of Jurkat lysate.

Anti-PDE1A Antibody (aa259-545, clone 5H4) - LS-C338815 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5H4
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDE1A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDE1A.

Anti-PDE1A Antibody (aa259-545, clone 7D5) - LS-C338812 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 7D5
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-PDE1A mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-PDE1A Antibody (aa212-535) - LS-C186226 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded MDAMB468 xenograft using PDE1A antibody at 1:500 dilution.

Anti-PDE1A Antibody (aa525-537) IHC-plus™ - LS-B9214 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-PDE1A antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PDE1A Antibody - NBP1-86009 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PDE1A Antibody [NBP1-86009] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

PDE1A Antibody - NBP1-51996 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: PDE1A Antibody [NBP1-51996] - Western blot analysis of PDE1A in Human Cerebellum lysate (35ug protein in RIPA buffer) using NBP1-51996 at 1ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

PDE1A Antibody - H00005136-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: PDE1A Antibody [H00005136-B01] - analysis of PDE1A expression in transfected 293T cell line by PDE1A MaxPab polyclonal antibody (B01). Lane 1: PDE1A transfected lysate (62.30 KDa). Lane 2: Non-transfected lysate.

PDE1A Antibody - H00005136-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PDE1A Antibody [H00005136-D01P] - Analysis of PDE1A expression in transfected 293T cell line by PDE1A polyclonal antibody.Lane 1: PDE1A transfected lysate(62.30 KDa).Lane 2: Non-transfected lysate.

PDE1A Antibody - H00005136-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PDE1A Antibody - H00005136-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: PDE1A Antibody [H00005136-B01P] - Analysis of PDE1A expression in transfected 293T cell line by PDE1A polyclonal antibody. Lane 1: PDE1A transfected lysate(59.95 KDa). Lane 2: Non-transfected lysate.

Anti-PDE1A antibody produced in mouse - SAB1409417 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PDE1A: <B>Cat. No. SAB1409417</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~60 kDa using PDE1A transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PDE1A (C-terminal) antibody produced in goat - SAB2501447 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PDE1A (C-terminal) <B>Cat. No. SAB2501447</B>: (1 μg/mL) staining of Human Cerebellum lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-PDE1A antibody produced in rabbit - HPA022151 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PDE1A: <B>Cat. No. HPA022151</B>: Immunohistochemical staining of human liver shows strong granular staining in hepatocytes.

Anti-PDE1A antibody produced in rabbit - AV53563 from Sigma-Aldrich

Prices $316.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: Jurkat (<B>Cat. No. AV53563</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type Jurkat

Anti-PDE1A (16-30) antibody produced in rabbit - SAB1100431 from Sigma-Aldrich

Prices $309.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-PDE1A (16-30), <B>Cat. No. SAB1100431</B>: Immunofluorescence of HUVEC cells using Anti-PDE1A (16-30), SAB1100431 (red), taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-PDE1A antibody produced in rabbit - SAB1410919 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PDE1A: <B>Cat. No. SAB1410919</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~62.3 kDa using PDE1A transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

PDE1A antibody - C-terminal region (ARP53625_P050) - ARP53625_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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