| Gene Symbol | PDE1A |
|---|---|
| Entrez Gene | 5136 |
| Alt Symbol | CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A |
| Species | Human |
| Gene Type | protein-coding |
| Description | phosphodiesterase 1A, calmodulin-dependent |
| Other Description | 61 kDa Cam-PDE|calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A|calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase|cam-PDE 1A |
| Swissprots | Q9C0L1 Q9C0L2 Q86VZ0 P54750 Q9C0L0 Q9C0K9 Q9UFX3 Q9C0K8 Q9C0L4 Q9C0L3 D3DPG5 |
| Accessions | AAD40741 AAY14812 AAY14837 BAB20049 BAB20050 BAB20051 BAB20052 BAB20053 BAB20054 BAB20055 BAB20056 BAB20057 EAX10965 EAX10966 EAX10967 EAX10968 EAX10969 EAX10970 EAX10971 EAX10972 EAX10973 EAX10974 EAX10975 P54750 AA846454 AB038227 BAB20037 AB038228 BAB20038 AF110235 AAD40737 AF110236 AAD40738 AF110237 AAD40739 AF110238 AAD40740 AF110240 AJ401610 CAC82208 AK130643 AK294239 BAH11712 AK295657 BAH12143 AK301720 BAH13538 AL110263 CAB53703 AL536937 BC022480 AAH22480 BC047057 BG196993 BM719913 DA128734 DA295167 DB128091 DB512285 DC396228 DQ892369 ABM83295 DQ893372 ABM84298 DQ895578 ABM86504 DQ896694 ABM87693 U40370 AAC50436 XM_011511323 XP_011509625 XM_011511324 XP_011509626 XM_011511325 XP_011509627 XM_011511326 XP_011509628 XR_922940 NM_001003683 NP_001003683 NM_001258312 NP_001245241 NM_001258313 NP_001245242 NM_001258314 NP_001245243 NM_005019 NP_005010 |
| Function | Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP. |
| Tissue Specificity | Several tissues, including brain, kidney, testes and heart. |
| Top Pathways | Taste transduction, Calcium signaling pathway, Morphine addiction, Purine metabolism |