CPSF7

Gene Symbol CPSF7
Entrez Gene 79869
Alt Symbol CFIm59
Species Human
Gene Type protein-coding
Description cleavage and polyadenylation specific factor 7, 59kDa
Other Description CPSF 59 kDa subunit|cleavage and polyadenylation specificity factor 59 kDa subunit|cleavage and polyadenylation specificity factor subunit 7|cleavage factor Im complex 59 kDa subunit|pre mRNA cleavage factor I, 59 kDa subunit|pre-mRNA cleavage factor I, 59 kDa subunit|pre-mRNA cleavage factor Im 59 kDa subunit
Swissprots Q9H9V1 C9K0Q4 B3KU04 Q8N684 Q9H025 Q7Z3H9
Accessions EAW73945 Q8N684 AJ275970 CAC81661 AK022591 BAB14118 AK092037 AK096343 BAG53266 AK294578 BAG57769 AK307190 AL512759 CAC21678 AL832546 AL832667 AL833332 BC018135 AAH18135 BX537888 CAD97884 DA194038 DA804579 EU831912 ACE87353 EU832006 ACE86669 XM_005274298 XP_005274355 XM_005274299 XP_005274356 XM_005274303 XP_005274360 XM_011545257 XP_011543559 XM_011545258 XP_011543560 XM_011545259 XP_011543561 XM_011545260 XP_011543562 XM_011545261 XP_011543563 XM_011545262 XP_011543564 XM_011545263 XP_011543565 NM_001136040 NP_001129512 NM_001142565 NP_001136037 NM_024811 NP_079087
Function Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Binds to cleavage and polyadenylation RNA substrates. {ECO:0000269|PubMed:8626397}.
Subcellular Location Nucleus {ECO:0000305|PubMed:20695905}.
Top Pathways mRNA surveillance pathway

CPSF7 (A-9) - sc-393880 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CPSF7 (A-9): sc-393880. Western blot analysis of CPSF7 expression in Jurkat (A), Hep G2 (B) and K-562 (C) whole cell lysates.

CPSF7 (P-20) - sc-79426 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CPSF7 (P-20): sc-79426. Western blot analysis of CPSF7 expression in Jurkat whole cell lysate.

CPSF7 (K-17) - sc-79424 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CPSF7 (K-17): sc-79424. Western blot analysis of CPSF7 expression in HeLa nuclear extract.

CPSF7 (H-53) - sc-292263 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-pre-mRNA cleavage factor I (59 kDa subunit) antibody - ab169626 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-pre-mRNA cleavage factor I (59 kDa subunit) antibody (ab169626) at 1 µg/mlLane 1 : pre-mRNA cleavage factor I (59 kDa subunit) transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-pre-mRNA cleavage factor I (59 kDa subunit) antibody - C-terminal - ab170792 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Flow cytometric analysis of K562 cells using ab170792 at a 1/10 dilution (right/green histogram) compared to a negative control cell (left/blue histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used .

Anti-pre-mRNA cleavage factor I (59 kDa subunit) antibody - ab50965 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Lane 1 : Lane 2 :  Anti-pre-mRNA cleavage factor I (59 kDa subunit) antibody (ab50965) at 1.25 µg/mlLane 1 : MarkerLane 2 : HepG2 cell lysate at 10 µgSecondaryLane 2 : HRP conjugated anti-Rabbit IgG at 1/50,000

Anti-pre-mRNA cleavage factor I (59 kDa subunit) antibody - ab84549 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of human pre-mRNA cleavage factor I (59 kDa subunit) by Immunohistochemistry.Sample: formalin fixed, paraffin embedded section of human breast carcinoma.Antibody: ab84549 used at a dilution of 1/250.Detection: DAB staining.

Anti-FLJ12529 / CPSF7 Antibody (aa427-455, AP) - LS-C234183 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FLJ12529 / CPSF7 Antibody (aa427-455, Biotin) - LS-C234184 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FLJ12529 / CPSF7 Antibody (aa427-455, FITC) - LS-C234185 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FLJ12529 / CPSF7 Antibody (aa427-455, APC) - LS-C234186 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FLJ12529 / CPSF7 Antibody (aa427-455, PE) - LS-C234188 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FLJ12529 / CPSF7 Antibody (aa1-50) - LS-C288168 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-FLJ12529 / CPSF7 Antibody (aa427-455, Azide-free, HRP) - LS-C249744 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FLJ12529 / CPSF7 Antibody (aa434-463) - LS-C320571 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FLJ12529 / CPSF7 Antibody - LS-C332718 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of HEK-293 cell line, using CPSF7 antibody.

Anti-FLJ12529 / CPSF7 Antibody (aa427-455) - LS-C167007 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CPSF7 Antibody western blot of K562 cell line lysates (35 ug/lane). The CPSF7 antibody detected the CPSF7 protein (arrow).

Anti-FLJ12529 / CPSF7 Antibody (aa175-225) - LS-C288170 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human CPSF59 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-CPSF59 used at a dilution of 1:500 (2 ug/ml). Detection: DAB.

Anti-FLJ12529 / CPSF7 Antibody (aa175-225) - LS-C286514 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human CPSF59 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-CPSF59 used at a dilution of 1:250.

Anti-FLJ12529 / CPSF7 Antibody (C-Terminus) IHC-plus™ - LS-B11465 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FLJ12529 / CPSF7 antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11465 concentration 10 ug/ml.

pre-mRNA cleavage factor I (59 kDa subunit) Antibody - NB100-61600 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: pre-mRNA cleavage factor I (59 kDa subunit) Antibody [NB100-61600] - Whole cell lysate (1 mg for IP,  20% of IP loaded) from HeLa cells.  Affinity purified  rabbit anti-CPSF59 antibody NB100-61600 used for IP at 3  mcg/mg lysate. CPSF59 was also immunoprecipitated by rabbit  anti-CPSF59 antibody NB100-61599, which recognizes an  upstream epitope.

pre-mRNA cleavage factor I (59 kDa subunit) Antibody - NBP1-89868 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: pre-mRNA cleavage factor I (59 kDa subunit) Antibody [NBP1-89868] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

pre-mRNA cleavage factor I (59 kDa subunit) Antibody - H00079869-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: pre-mRNA cleavage factor I (59 kDa subunit) Antibody [H00079869-B01] - analysis of FLJ12529 expression in transfected 293T cell line by FLJ12529 MaxPab polyclonal antibody (B01). Lane 1: FLJ12529 transfected lysate (52.00 KDa). Lane 2: Non-transfected lysate.

pre-mRNA cleavage factor I (59 kDa subunit) Antibody - NB100-61599 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: pre-mRNA cleavage factor I (59 kDa subunit) Antibody [NB100-61599] - Detection of Human CPSF59 on HeLa whole cell lysate using NB100-61599. CPSF59  was also immunoprecipitated by rabbit anti-CPSF59 antibody NB100-61600.
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