Gene Symbol | FOXI1 |
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Entrez Gene | 2299 |
Alt Symbol | FKH10, FKHL10, FREAC-6, FREAC6, HFH-3, HFH3 |
Species | Human |
Gene Type | protein-coding |
Description | forkhead box I1 |
Other Description | HNF-3/fork-head homolog 3|HNF-3/fork-head homolog-3|forkhead box protein I1|forkhead-like 10|forkhead-related activator 6|forkhead-related protein FKHL10|forkhead-related transcription factor 6|hepatocyte nuclear factor 3 forkhead homolog 3 |
Swissprots | Q8N6L8 Q66SR7 Q14518 Q12951 |
Accessions | AAA92041 ADN03217 ADN03218 ADN03219 ADN03220 ADN03221 ADN03222 ADN03223 ADN03224 ADN03225 ADN03226 ADN03227 ADN03228 ADN03229 ADN03230 ADN03231 ADN03232 ADN03233 ADN03234 ADN03235 ADN03236 ADN03237 ADN03238 ADN03239 ADN03240 ADN03241 ADN03242 ADN03243 ADN03244 ADN03245 ADN03246 ADN03247 ADN03248 ADN03249 ADN03250 ADN03251 ADN03252 ADN03253 ADN03254 ADN03255 ADN03256 ADN03257 ADN03258 ADN03259 ADN03260 ADN03261 ADN03262 ADN03263 ADN03264 ADN03265 ADN03266 ADN03267 ADN03268 ADN03269 ADN03270 ADN03271 ADN03272 ADN03273 ADN03274 ADN03275 ADN03276 ADN03277 ADN03278 ADN03279 ADN03280 ADN03281 ADN03282 ADN03283 ADN03284 ADN03285 ADN03286 ADN03287 ADN03288 ADN03289 ADN03290 ADN03291 ADN03292 ADN03293 ADN03294 ADN03295 ADN03296 ADN03297 ADN03298 ADN03299 ADN03300 ADN03301 ADN03302 ADN03303 ADN03304 ADN03305 ADN03306 ADN03307 ADN03308 ADN03309 ADN03310 ADN03311 ADN03312 ADN03313 ADN03314 ADN03315 ADN03316 ADN03317 ADN03318 ADN03319 ADN03320 ADN03321 ADN03322 ADN03323 ADN03324 ADN03325 ADN03326 ADN03327 ADN03328 ADN03329 ADN03330 ADN03331 ADN03332 ADN03333 ADN03334 ADN03335 ADN03336 EAW61489 EAW61490 Q12951 AK292176 BAF84865 AY707089 AAU12169 BC029778 AAH29778 L13203 AAB50574 XR_941092 NM_012188 NP_036320 NM_144769 NP_658982 |
Function | Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Expressed in kidney. |
FOXI1 CRISPR/Cas9 KO Plasmid (h) - sc-408728 from Santa Cruz Biotechnology
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FOXI1 HDR Plasmid (h) - sc-408728-HDR from Santa Cruz Biotechnology
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FOXI1 Double Nickase Plasmid (h) - sc-408728-NIC from Santa Cruz Biotechnology
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FOXI1 Double Nickase Plasmid (h2) - sc-408728-NIC-2 from Santa Cruz Biotechnology
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FOXI1 CRISPR Activation Plasmid (h) - sc-408728-ACT from Santa Cruz Biotechnology
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FOXI1 CRISPR Activation Plasmid (h2) - sc-408728-ACT-2 from Santa Cruz Biotechnology
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FOXI1 Lentiviral Activation Particles (h) - sc-408728-LAC from Santa Cruz Biotechnology
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FOXI1 Lentiviral Activation Particles (h2) - sc-408728-LAC-2 from Santa Cruz Biotechnology
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FOXI1 siRNA (h) - sc-75052 from Santa Cruz Biotechnology
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FOXI1 shRNA Plasmid (h) - sc-75052-SH from Santa Cruz Biotechnology
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FOXI1 shRNA (h) Lentiviral Particles - sc-75052-V from Santa Cruz Biotechnology
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FOXI1 RNAi - H00002299-R02 from Novus Biologicals
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MISSION® esiRNA - EHU031711 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8897 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8897 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08088 from Sigma-Aldrich
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FOXI1 siRNA (Human) - CRH1606 from Cohesion Biosciences
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FOXI1 RNAi - H00002299-R01 from Novus Biologicals
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FOXI1 - MBS827575 from MyBioSource
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shRNA set against Human FOXI1 (NM_012188.4) - SHH296581 from Creative biogene
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shRNA set against Human FOXI1(NM_144769.2) - SHH066449 from Creative biogene
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Human FOXI1 siRNA - orb262108 from Biorbyt
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FOXI1 shRNA Plasmid (Human) - CHH1606 from Cohesion Biosciences
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FOXI1 miRNA 3'UTR clone - MiUTR1H-03823 from Creative biogene
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FOXI1 miRNA 3'UTR clone - MiUTR3H-03867 from Creative biogene
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