Gene Symbol | OXGR1 |
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Entrez Gene | 27199 |
Alt Symbol | GPR80, GPR99, P2RY15, P2Y15, aKGR |
Species | Human |
Gene Type | protein-coding |
Description | oxoglutarate (alpha-ketoglutarate) receptor 1 |
Other Description | 2-oxoglutarate receptor 1|G protein-coupled receptor 80|G protein-coupled receptor 99|G-protein coupled receptor 80|G-protein coupled receptor 99|P2Y purinoceptor 15|P2Y-like GPCR|P2Y-like nucleotide receptor|alpha-ketoglutarate receptor 1|oxoglutarate receptor 1|seven transmembrane helix receptor |
Swissprots | Q96P68 Q5T5A7 Q86TL1 |
Accessions | AAL26480 BAB89311 BAC06095 CAD38348 CAD69266 CAG26849 EAX08964 Q96P68 AF370886 AAM76912 AJ305372 CAC83857 AK122639 BAG53633 AK313684 BAG36433 BC103881 AAI03882 BC103882 AAI03883 BC103883 AAI03884 JQ308179 AFF59489 XM_005254043 XP_005254100 XM_005254044 XP_005254101 XM_005254045 XP_005254102 XM_005254046 XP_005254103 XM_011521077 XP_011519379 NM_080818 NP_543008 |
Function | Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Detected in kidney and, to a lower extend, in placenta. Not detected in brain tissues including the frontal cortex, caudate putamen, thalamus, hypothalamus, hippocampus or pons. |
GPR80 CRISPR/Cas9 KO Plasmid (h) - sc-404698 from Santa Cruz Biotechnology
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GPR80 HDR Plasmid (h) - sc-404698-HDR from Santa Cruz Biotechnology
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GPR80 Double Nickase Plasmid (h) - sc-404698-NIC from Santa Cruz Biotechnology
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GPR80 Double Nickase Plasmid (h2) - sc-404698-NIC-2 from Santa Cruz Biotechnology
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GPR80 CRISPR Activation Plasmid (h) - sc-404698-ACT from Santa Cruz Biotechnology
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GPR80 CRISPR Activation Plasmid (h2) - sc-404698-ACT-2 from Santa Cruz Biotechnology
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GPR80 Lentiviral Activation Particles (h) - sc-404698-LAC from Santa Cruz Biotechnology
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GPR80 Lentiviral Activation Particles (h2) - sc-404698-LAC-2 from Santa Cruz Biotechnology
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GPR80 siRNA (h) - sc-75189 from Santa Cruz Biotechnology
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GPR80 shRNA Plasmid (h) - sc-75189-SH from Santa Cruz Biotechnology
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GPR80 shRNA (h) Lentiviral Particles - sc-75189-V from Santa Cruz Biotechnology
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OXGR1/GPR80/P2Y15 RNAi - H00027199-R02 from Novus Biologicals
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MISSION® esiRNA - EHU143971 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16217 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16217 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07535 from Sigma-Aldrich
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OXGR1 siRNA (Human) - CRH9020 from Cohesion Biosciences
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shRNA set against Human OXGR1 (NM_080818.3) - SHH369340 from Creative biogene
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shRNA set against Human OXGR1(NM_080818.3) - SHR084246 from Creative biogene
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OXGR1 shRNA Plasmid (Human) - CHH9020 from Cohesion Biosciences
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OXGR1 miRNA 3'UTR clone - MiUTR1H-07428 from Creative biogene
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