Gene Symbol | MS4A1 |
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Entrez Gene | 931 |
Alt Symbol | B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7 |
Species | Human |
Gene Type | protein-coding |
Description | membrane-spanning 4-domains, subfamily A, member 1 |
Other Description | B-lymphocyte antigen CD20|B-lymphocyte cell-surface antigen B1|CD20 antigen|CD20 receptor|leukocyte surface antigen Leu-16 |
Swissprots | P08984 Q13963 B4DT24 A6NMS4 P11836 |
Accessions | AAA35581 AAA88911 CCA94567 EAW73889 EAW73890 EAW73891 EAW73892 P11836 AK225630 AK292168 BAF84857 AK300025 BAG61836 AK310118 AW504475 BC002807 AAH02807 CD691924 DQ893507 ABM84433 DQ896499 ABM87498 X07203 CAA30179 X07204 CAA30180 X12530 CAA31046 NM_021950 NP_068769 NM_152866 NP_690605 |
Function | This protein may be involved in the regulation of B-cell activation and proliferation. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:22615937}; Multi-pass membrane protein {ECO:0000269|PubMed:22615937}. Cell membrane {ECO:0000269|PubMed:22615937}; Lipid-anchor {ECO:0000269|PubMed:22615937}. |
Tissue Specificity | Expressed on B-cells. |
Top Pathways | Hematopoietic cell lineage |
CD20 CRISPR/Cas9 KO Plasmid (h) - sc-416765 from Santa Cruz Biotechnology
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CD20 HDR Plasmid (h) - sc-416765-HDR from Santa Cruz Biotechnology
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CD20 Double Nickase Plasmid (h) - sc-416765-NIC from Santa Cruz Biotechnology
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CD20 Double Nickase Plasmid (h2) - sc-416765-NIC-2 from Santa Cruz Biotechnology
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CD20 CRISPR Activation Plasmid (h) - sc-416765-ACT from Santa Cruz Biotechnology
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CD20 CRISPR Activation Plasmid (h2) - sc-416765-ACT-2 from Santa Cruz Biotechnology
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CD20 Lentiviral Activation Particles (h) - sc-416765-LAC from Santa Cruz Biotechnology
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CD20 Lentiviral Activation Particles (h2) - sc-416765-LAC-2 from Santa Cruz Biotechnology
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CD20 siRNA (h) - sc-29972 from Santa Cruz Biotechnology
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CD20 shRNA Plasmid (h) - sc-29972-SH from Santa Cruz Biotechnology
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CD20 shRNA (h) Lentiviral Particles - sc-29972-V from Santa Cruz Biotechnology
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CD20 RNAi - H00000931-R04 from Novus Biologicals
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MS4A1/CD20 RNAi - H00000931-R03 from Novus Biologicals
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Fc epsilon RI beta/MS4A2 RNAi - H00002206-R01 from Novus Biologicals
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MISSION® esiRNA - EHU129481 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14627 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14627 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11136 from Sigma-Aldrich
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MS4A1 siRNA (Human) - CRH0658 from Cohesion Biosciences
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shRNA set against Human MS4A1 (NM_021950.3) - SHH345448 from Creative biogene
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shRNA set against Human MS4A1(NM_021950.3) - SHH202817 from Creative biogene
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Human MS4A1 siRNA - orb261160 from Biorbyt
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MS4A1 shRNA Plasmid (Human) - CHH0658 from Cohesion Biosciences
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MS4A1 miRNA 3'UTR clone - MiUTR1H-06462 from Creative biogene
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