Gene Symbol | MAG |
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Entrez Gene | 4099 |
Alt Symbol | GMA, S-MAG, SIGLEC-4A, SIGLEC4A |
Species | Human |
Gene Type | protein-coding |
Description | myelin associated glycoprotein |
Other Description | myelin-associated glycoprotein|sialic acid binding Ig-like lectin 4A|sialic acid-binding immunoglobulin-like lectin 4A |
Swissprots | F5GYC0 P20916 B7Z2E5 Q567S4 |
Accessions | AAB58805 P20916 AK094545 AK222649 BAD96369 AK222680 BAD96400 AK223562 BAD97282 AK294644 BAH11831 AK308976 BC034042 BC053347 AAH53347 BC093045 AAH93045 BI755065 DC331168 M29273 AAA59545 X98405 CAA67055 NM_001199216 NP_001186145 NM_002361 NP_002352 NM_080600 NP_542167 |
Function | Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3- linked sialic acid (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Cell adhesion molecules (CAMs) |
MAG CRISPR/Cas9 KO Plasmid (h) - sc-401604 from Santa Cruz Biotechnology
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MAG HDR Plasmid (h) - sc-401604-HDR from Santa Cruz Biotechnology
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MAG Double Nickase Plasmid (h) - sc-401604-NIC from Santa Cruz Biotechnology
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MAG Double Nickase Plasmid (h2) - sc-401604-NIC-2 from Santa Cruz Biotechnology
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MAG CRISPR Activation Plasmid (h) - sc-401604-ACT from Santa Cruz Biotechnology
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MAG CRISPR Activation Plasmid (h2) - sc-401604-ACT-2 from Santa Cruz Biotechnology
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MAG Lentiviral Activation Particles (h) - sc-401604-LAC from Santa Cruz Biotechnology
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MAG Lentiviral Activation Particles (h2) - sc-401604-LAC-2 from Santa Cruz Biotechnology
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MAG siRNA (h) - sc-35841 from Santa Cruz Biotechnology
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MAG shRNA Plasmid (h) - sc-35841-SH from Santa Cruz Biotechnology
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MAG shRNA (h) Lentiviral Particles - sc-35841-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU141201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12908 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12908 from Sigma-Aldrich
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MAG siRNA (Human) - CRH2779 from Cohesion Biosciences
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shRNA set against Human MAG (NM_002361.3) - SHH336691 from Creative biogene
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Human MAG siRNA - orb263281 from Biorbyt
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MAG shRNA Plasmid (Human) - CHH2779 from Cohesion Biosciences
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MAG miRNA 3'UTR clone - MiUTR3H-01460 from Creative biogene
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MAG miRNA 3'UTR clone - MiUTR3H-01461 from Creative biogene
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