| Gene Symbol | EMILIN1 |
|---|---|
| Entrez Gene | 11117 |
| Alt Symbol | EMI, EMILIN, gp115 |
| Species | Human |
| Gene Type | protein-coding |
| Description | elastin microfibril interfacer 1 |
| Other Description | EMILIN-1|elastin microfibril interface located protein|elastin microfibril interface-located protein 1 |
| Swissprots | Q96IH6 Q9UG76 Q53SY9 H0Y7A0 A5PL03 Q9Y6C2 Q96G58 |
| Accessions | AAF25006 AAX93166 EAX00644 EAX00645 EAX00646 EAX00647 Q9Y6C2 AF088916 AAD42161 AK075517 AK307539 AL050138 CAB43287 AL552691 BC007530 AAH07530 BC009947 AAH09947 BC017284 BC090957 BC136279 AAI36280 BC142638 BC142688 AAI42689 CN350368 XM_006711928 XP_006711991 NM_007046 NP_008977 |
| Function | May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity. |
| Subcellular Location | Secreted, extracellular space, extracellular matrix. Note=Found mainly at the interface between amorphous elastin and microfibrils. |
| Tissue Specificity | Distributed in tissues where resilience and elastic recoil are prominent. Highest levels in the adult small intestine, aorta, lung, uterus, and appendix and in the fetal spleen, kidney, lung, and heart; intermediate expression was detected in adult liver, ovary, colon, stomach, lymph node and spleen; adult heart, bladder, prostate, adrenal gland, mammary gland, placenta and kidney showed low expression whereas a series of other adult tissues, including skeletal muscle and different regions of adult brain show no expression. {ECO:0000269|PubMed:11278945}. |
EMILIN-1 CRISPR/Cas9 KO Plasmid (h) - sc-403434 from Santa Cruz Biotechnology
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EMILIN-1 HDR Plasmid (h) - sc-403434-HDR from Santa Cruz Biotechnology
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EMILIN-1 Double Nickase Plasmid (h) - sc-403434-NIC from Santa Cruz Biotechnology
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EMILIN-1 Double Nickase Plasmid (h2) - sc-403434-NIC-2 from Santa Cruz Biotechnology
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EMILIN-1 CRISPR Activation Plasmid (h) - sc-403434-ACT from Santa Cruz Biotechnology
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EMILIN-1 CRISPR Activation Plasmid (h2) - sc-403434-ACT-2 from Santa Cruz Biotechnology
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EMILIN-1 Lentiviral Activation Particles (h) - sc-403434-LAC from Santa Cruz Biotechnology
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EMILIN-1 Lentiviral Activation Particles (h2) - sc-403434-LAC-2 from Santa Cruz Biotechnology
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EMILIN-1 siRNA (h) - sc-60016 from Santa Cruz Biotechnology
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EMILIN-1 shRNA Plasmid (h) - sc-60016-SH from Santa Cruz Biotechnology
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EMILIN-1 shRNA (h) Lentiviral Particles - sc-60016-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN7841 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7841 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02896 from Sigma-Aldrich
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EMILIN1 siRNA (Human) - CRH7603 from Cohesion Biosciences
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EMILIN1 RNAi - H00011117-R01 from Novus Biologicals
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EMILIN1 - MBS8201965 from MyBioSource
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shRNA set against Human EMILIN1 (NM_007046.3) - SHH285469 from Creative biogene
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Human EMILIN1 siRNA - orb268105 from Biorbyt
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EMILIN1 shRNA Plasmid (Human) - CHH7603 from Cohesion Biosciences
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EMILIN1 miRNA 3'UTR clone - MiUTR3H-00720 from Creative biogene
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