Gene Symbol | FCER2 |
---|---|
Entrez Gene | 2208 |
Alt Symbol | BLAST-2, CD23, CD23A, CLEC4J, FCE2, IGEBF |
Species | Human |
Gene Type | protein-coding |
Description | Fc fragment of IgE, low affinity II, receptor for (CD23) |
Other Description | C-type lectin domain family 4, member J|CD23 antigen|fc-epsilon-RII|immunoglobulin E-binding factor|low affinity immunoglobulin epsilon Fc receptor|lymphocyte IgE receptor |
Swissprots | P06734 |
Accessions | AAA52433 AAB35925 AAB35926 EAW69004 EAW69005 EAW69006 EAW69007 EAW69008 EAW69009 EAW69010 EAW69011 P06734 AK223207 BAD96927 AK310071 AK310707 BC014108 AAH14108 BC062591 AAH62591 BC064417 DA957269 DB333832 DQ892235 ABM83161 EU176675 ABW03476 M14766 AAA52435 M15059 AAA52434 X04772 CAA28465 XM_005272462 XP_005272519 NM_001207019 NP_001193948 NM_001220500 NP_001207429 NM_002002 NP_001993 |
Function | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). |
Subcellular Location | Cell membrane; Single-pass type II membrane protein. Cell membrane; Lipid-anchor. Secreted. Note=Also exists as a soluble excreted form, sCD23. |
Top Pathways | Hematopoietic cell lineage, Epstein-Barr virus infection |