Gene Symbol |
SLIT3
|
Entrez Gene |
6586
|
Alt Symbol |
MEGF5, SLIL2, SLIT1, Slit-3, slit2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
slit homolog 3 (Drosophila)
|
Other Description |
multiple EGF-like domains protein 5|multiple epidermal growth factor-like domains protein 5|slit homolog 3 protein
|
Swissprots |
J3KNP3 O95804 Q9UFH5 O75094 A6H8U9
|
Accessions |
CCQ43196 EAW61499 EAW61500 EAW61501 O75094 AB011538 BAA32466 AB017169 BAA35186 AF075240 AAD19336 AF086552 AI741785 AK001626 AK310549 AL122074 CAB59249 AY358884 AAQ89243 BC062365 BC098388 BC142665 BC142717 BC146759 AAI46760 HY285022 NM_001271946 NP_001258875 NM_003062 NP_003053
|
Function |
May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.
|
Subcellular Location |
Secreted {ECO:0000250}.
|
Tissue Specificity |
Predominantly expressed in thyroid. {ECO:0000269|PubMed:9813312}.
|
Top Pathways |
Axon guidance
|