Gene Symbol | HADHA |
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Entrez Gene | 3030 |
Alt Symbol | ECHA, GBP, HADH, LCEH, LCHAD, MTPA, TP-ALPHA |
Species | Human |
Gene Type | protein-coding |
Description | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit |
Other Description | 3-ketoacyl-Coenzyme A (CoA) thiolase, alpha subunit|3-oxoacyl-CoA thiolase|78 kDa gastrin-binding protein|gastrin-binding protein|hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit|long-chain 2-enoyl-CoA hydratase|long-chain-3-hydroxyacyl-CoA dehydrogenase|mitochondrial long-chain 2-enoyl-Coenzyme A (CoA) hydratase, alpha subunit|mitochondrial long-chain L-3-hydroxyacyl-Coenzyme A (CoA) dehydrogenase, alpha subunit|mitochondrial trifunctional enzyme, alpha subunit|mitochondrial trifunctional protein, alpha subunit|trifunctional enzyme subunit alpha, mitochondrial |
Swissprots | B4DYP2 Q16679 Q9UQC5 Q53T69 Q96GT7 B2R7L4 Q53TA2 P40939 |
Accessions | AAX93141 AAY14643 BAA76735 EAX00703 EAX00704 P40939 AI972144 AK293398 BAG56906 AK299258 BAG61288 AK302532 BAG63804 AK313027 BAG35861 BC009235 AAH09235 CN264228 D16480 BAA03941 DQ892776 ABM83702 DQ896023 ABM87022 FJ626228 GU727642 ADU87643 U04627 AAA56664 NM_000182 NP_000173 |
Function | Bifunctional subunit. |
Subcellular Location | Mitochondrion. |
Top Pathways | Biosynthesis of unsaturated fatty acids, Tryptophan metabolism, Fatty acid degradation, Fatty acid elongation, Carbon metabolism |
HADHA CRISPR/Cas9 KO Plasmid (h) - sc-402803 from Santa Cruz Biotechnology
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HADHA HDR Plasmid (h) - sc-402803-HDR from Santa Cruz Biotechnology
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HADHA Double Nickase Plasmid (h) - sc-402803-NIC from Santa Cruz Biotechnology
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HADHA Double Nickase Plasmid (h2) - sc-402803-NIC-2 from Santa Cruz Biotechnology
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HADHA CRISPR Activation Plasmid (h) - sc-402803-ACT from Santa Cruz Biotechnology
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HADHA CRISPR Activation Plasmid (h2) - sc-402803-ACT-2 from Santa Cruz Biotechnology
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HADHA Lentiviral Activation Particles (h) - sc-402803-LAC from Santa Cruz Biotechnology
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HADHA Lentiviral Activation Particles (h2) - sc-402803-LAC-2 from Santa Cruz Biotechnology
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HADHA siRNA (h) - sc-75220 from Santa Cruz Biotechnology
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HADHA shRNA Plasmid (h) - sc-75220-SH from Santa Cruz Biotechnology
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HADHA shRNA (h) Lentiviral Particles - sc-75220-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU023961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1642 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1642 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05419 from Sigma-Aldrich
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HADHA siRNA (Human) - CRH2059 from Cohesion Biosciences
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HADHA - MBS8231118 from MyBioSource
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shRNA set against Human HADHA (NM_000182.4) - SHH310149 from Creative biogene
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shRNA set against Human HADHA(NM_000182.4) - SHH113213 from Creative biogene
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Human HADHA siRNA - orb262561 from Biorbyt
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HADHA shRNA Plasmid (Human) - CHH2059 from Cohesion Biosciences
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HADHA miRNA 3'UTR clone - MiUTR3H-03715 from Creative biogene
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