Gene Symbol | Il17a |
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Entrez Gene | 16171 |
Alt Symbol | Ctla-8, Ctla8, IL-17, IL-17A, Il17 |
Species | Mouse |
Gene Type | protein-coding |
Description | interleukin 17A |
Other Description | cytotoxic T-lymphocyte-associated antigen 8|interleukin-17A |
Swissprots | Q62386 Q60971 |
Accessions | AAA93253 CAV28591 CBH19851 EDL14378 Q62386 AK040420 BAC30590 BC119303 AAI19304 BC119309 AAI19310 U43088 AAB05222 NM_010552 NP_034682 |
Function | Induces stromal cells to produce proinflammatory and hematopoietic cytokines. {ECO:0000250}. |
Subcellular Location | Secreted. |
Tissue Specificity | Restricted to a subset of activated T-cells. {ECO:0000269|PubMed:16990136}. |
Top Pathways | Cytokine-cytokine receptor interaction, Rheumatoid arthritis, Inflammatory bowel disease (IBD) |
IL-17 CRISPR/Cas9 KO Plasmid (m) - sc-421092 from Santa Cruz Biotechnology
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IL-17 HDR Plasmid (m) - sc-421092-HDR from Santa Cruz Biotechnology
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IL-17 Double Nickase Plasmid (m) - sc-421092-NIC from Santa Cruz Biotechnology
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IL-17 Double Nickase Plasmid (m2) - sc-421092-NIC-2 from Santa Cruz Biotechnology
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IL-17 CRISPR Activation Plasmid (m) - sc-421092-ACT from Santa Cruz Biotechnology
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IL-17 CRISPR Activation Plasmid (m2) - sc-421092-ACT-2 from Santa Cruz Biotechnology
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IL-17 Lentiviral Activation Particles (m) - sc-421092-LAC from Santa Cruz Biotechnology
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IL-17 Lentiviral Activation Particles (m2) - sc-421092-LAC-2 from Santa Cruz Biotechnology
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IL-17 siRNA (m) - sc-39650 from Santa Cruz Biotechnology
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IL-17 shRNA Plasmid (m) - sc-39650-SH from Santa Cruz Biotechnology
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IL-17 shRNA (m) Lentiviral Particles - sc-39650-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN33743 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33743 from Sigma-Aldrich
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IL17A siRNA (Mouse) - CRM2045 from Cohesion Biosciences
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IL17A - MBS8236636 from MyBioSource
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shRNA set against Mouse IL17A (NM_010552.3) - SHH318297 from Creative biogene
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shRNA set against Mouse Il17a(NM_010552.3) - SHL171252 from Creative biogene
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Mouse IL17A siRNA - orb281521 from Biorbyt
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IL17A shRNA Plasmid (Mouse) - CHM2045 from Cohesion Biosciences
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IL17A miRNA 3'UTR clone - MiUTR1M-05973 from Creative biogene
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