| Gene Symbol |
CCT4
|
| Entrez Gene |
10575
|
| Alt Symbol |
CCT-DELTA, Cctd, SRB
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chaperonin containing TCP1, subunit 4 (delta)
|
| Other Description |
T-complex protein 1 subunit delta|TCP-1-delta|chaperonin containing t-complex polypeptide 1, delta subunit|stimulator of TAR RNA-binding
|
| Swissprots |
Q96C51 O14870 F5H5W3 P50991 Q53QP9 B7Z8B1 B2R6I3
|
| Accessions |
AAY24140 EAW99984 EAW99985 EAW99986 EAW99987 P50991 AA136129 AF026291 AAC96010 AI439570 AK129860 AK290538 BAF83227 AK294665 BAH11840 AK295330 BAH12034 AK303082 BAH13897 AK307856 AK308942 AK312586 BAG35480 AK315975 BAH14346 AL555753 AU128145 BC014676 AAH14676 BC093446 BC106933 AAI06934 BC106934 AAI06935 BM765256 CD369623 DB461009 EU446763 ABZ92292 U38846 AAC50384 NM_001256721 NP_001243650 NM_006430 NP_006421
|
| Function |
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. {ECO:0000269|PubMed:20080638}.
|
| Subcellular Location |
Cytoplasm. Melanosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
|
![Western Blot: TCP1-delta Overexpression Lysate (Adult Normal) [NBL1-08901] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TCP1-delta.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3244_TCP1-delta%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08901-img0002.jpg)