| Gene Symbol |
ZNF274
|
| Entrez Gene |
10782
|
| Alt Symbol |
HFB101, ZF2, ZKSCAN19, ZSCAN51
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc finger protein 274
|
| Other Description |
KRAB zinc finger protein HFB101|neurotrophin receptor-interacting factor homolog|zinc finger protein HFB101|zinc finger protein with KRAB and SCAN domains 19|zinc finger protein zfp2
|
| Swissprots |
Q96GC6 Q92969 Q6MZG1 Q9UII0 Q9UII1 Q8WY37 Q53XU4 Q8WY38
|
| Accessions |
EAW72565 EAW72566 EAW72567 Q96GC6 AB029149 BAA88522 AB029150 BAA88523 AF275680 AAG24390 AF275681 AAG24391 AK022328 AK095162 AK222855 AK222878 AK295036 BAG58090 AK296929 BAG59481 AK297466 BAG59888 AK307906 AK316429 BAH14800 BC009763 AAH09763 BT007304 AAP35968 BX641169 CAE46074 CA942346 DA050458 DC362701 DC366107 U71598 AAB16810 XM_011526325 XP_011524627 XM_011526326 XP_011524628 XM_011526327 XP_011524629 XM_011526328 XP_011524630 XM_011526329 XP_011524631 NM_001278734 NP_001265663 NM_016324 NP_057408 NM_016325 NP_057409 NM_133502 NP_598009 NM_001278735
|
| Function |
Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin- modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression. {ECO:0000269|PubMed:10777669}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Nucleus, nucleolus {ECO:0000269|PubMed:10777669}.
|
| Top Pathways |
Neurotrophin signaling pathway
|