| Gene Symbol |
PIGT
|
| Entrez Gene |
51604
|
| Alt Symbol |
CGI-06, MCAHS3, NDAP, PNH2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphatidylinositol glycan anchor biosynthesis, class T
|
| Other Description |
GPI transamidase component PIG-T|GPI transamidase subunit|neurotrophin-regulated neuronal development-associated protein|phosphatidylinositol-glycan biosynthesis class T protein
|
| Swissprots |
Q9BQY8 Q9BQY7 Q7Z3N7 Q2NL69 B2RND5 Q9Y2Z5 B7Z3N1 E1P622 G8JLF5 Q9UJG6 Q969N2 B7Z7I8
|
| Accessions |
CAI72142 EAW75841 EAW75842 EAW75843 EAW75844 EAW75845 EAW75846 Q969N2 AB057724 BAB60854 AF058295 AF132940 AAD27715 AF305815 AAK55518 AK075469 BAC11639 AK225517 AK293294 BAH11487 AK293686 BAH11569 AK296063 BAH12247 AK296139 BAH12267 AK297830 BAH12673 AK299013 BAH12928 AK301815 BAH13561 AK302093 BAH13624 AK311100 AK311416 AK311492 AK311520 AK311522 AK316358 BAH14729 AL121742 CAB57341 AY358588 AAQ88951 BC015022 AAH15022 BC110892 AAI10893 BC136827 AAI36828 BC136828 AAI36829 BP392024 BX537612 CAD97799 DA037291 DC384944 DC399420 XM_005260430 XP_005260487 XM_005260432 XP_005260489 NM_001184728 NP_001171657 NM_001184729 NP_001171658 NM_001184730 NP_001171659 NM_015937 NP_057021 NR_047691 NR_047692 NR_047693 NR_047694 NR_047695
|
| Function |
Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates. {ECO:0000269|PubMed:11483512}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:11483512}; Single-pass type I membrane protein {ECO:0000269|PubMed:11483512}.
|
| Top Pathways |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
|
![Western Blot: PIGT Overexpression Lysate (Adult Normal) [NBP2-07107] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PIGT.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1759_PIGT%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07107-img0001.jpg)