Gene Symbol | VAMP4 |
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Entrez Gene | 8674 |
Alt Symbol | VAMP-4, VAMP24 |
Species | Human |
Gene Type | protein-coding |
Description | vesicle-associated membrane protein 4 |
Other Description | - |
Swissprots | Q96J20 Q9UEL7 O75379 Q96IY9 A2IDD8 |
Accessions | EAW90904 EAW90905 EAW90906 EAW90907 EAW90908 EAW90909 O75379 AF044310 AAC24032 AF052100 AK056124 AK123624 AK290441 BAF83130 AL035296 CAA22896 BC005974 AAH05974 BC007019 AAH07019 BC031264 AAH31264 CR457011 CAG33292 DB167275 XR_426805 NM_001185127 NP_001172056 NM_003762 NP_003753 NR_033704 NM_201994 |
Function | Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule. |
Subcellular Location | Golgi apparatus, trans-Golgi network membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}. Note=Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles. |
Top Pathways | SNARE interactions in vesicular transport |
VAMP-4 CRISPR/Cas9 KO Plasmid (h) - sc-404490 from Santa Cruz Biotechnology
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VAMP-4 HDR Plasmid (h) - sc-404490-HDR from Santa Cruz Biotechnology
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VAMP-4 Double Nickase Plasmid (h) - sc-404490-NIC from Santa Cruz Biotechnology
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VAMP-4 Double Nickase Plasmid (h2) - sc-404490-NIC-2 from Santa Cruz Biotechnology
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VAMP-4 CRISPR Activation Plasmid (h) - sc-404490-ACT from Santa Cruz Biotechnology
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VAMP-4 CRISPR Activation Plasmid (h2) - sc-404490-ACT-2 from Santa Cruz Biotechnology
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VAMP-4 Lentiviral Activation Particles (h) - sc-404490-LAC from Santa Cruz Biotechnology
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VAMP-4 Lentiviral Activation Particles (h2) - sc-404490-LAC-2 from Santa Cruz Biotechnology
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VAMP-4 siRNA (h) - sc-61766 from Santa Cruz Biotechnology
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VAMP-4 shRNA Plasmid (h) - sc-61766-SH from Santa Cruz Biotechnology
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VAMP-4 shRNA (h) Lentiviral Particles - sc-61766-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU000731 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22633 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22633 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10246 from Sigma-Aldrich
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VAMP4 siRNA (Human) - CRH5708 from Cohesion Biosciences
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VAMP4 - MBS8225702 from MyBioSource
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shRNA set against Human VAMP4 (NM_003762.4) - SHH442164 from Creative biogene
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Human VAMP4 siRNA - orb266210 from Biorbyt
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VAMP4 shRNA Plasmid (Human) - CHH5708 from Cohesion Biosciences
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VAMP4 miRNA 3'UTR clone - MiUTR3H-08813 from Creative biogene
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