Gene Symbol | ADCY3 |
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Entrez Gene | 109 |
Alt Symbol | AC3 |
Species | Human |
Gene Type | protein-coding |
Description | adenylate cyclase 3 |
Other Description | AC-III|ATP pyrophosphate-lyase 3|adenylate cyclase type 3|adenylate cyclase type III|adenylate cyclase, olfactive type|adenylyl cyclase 3|adenylyl cyclase, type III |
Swissprots | Q9UDB1 Q53T54 O60266 B3KT86 |
Accessions | AAY14787 EAX00739 EAX00740 EAX00741 O60266 AB011083 BAA25437 AF033861 AAD13403 AK027857 BAG51385 AK075424 BAC11613 AK095173 BAG52998 AK122926 BAG53802 BC020148 BC126235 AAI26236 BC144119 AAI44120 DA864173 HQ258684 ADR83435 XM_005264104 XP_005264161 XM_005264105 XP_005264162 XM_006711925 XP_006711988 XM_011532489 XP_011530791 XM_011532490 XP_011530792 XM_011532491 XP_011530793 XM_011532492 XP_011530794 XM_011532493 XP_011530795 XM_011532494 XP_011530796 XM_011532495 XP_011530797 XM_011532496 XP_011530798 NM_004036 NP_004027 |
Function | Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle. |
Top Pathways | Inflammatory mediator regulation of TRP channels, Oxytocin signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Vibrio cholerae infection |
A cyclase III CRISPR/Cas9 KO Plasmid (h) - sc-400407 from Santa Cruz Biotechnology
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A cyclase III HDR Plasmid (h) - sc-400407-HDR from Santa Cruz Biotechnology
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A cyclase III Double Nickase Plasmid (h) - sc-400407-NIC from Santa Cruz Biotechnology
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A cyclase III Double Nickase Plasmid (h2) - sc-400407-NIC-2 from Santa Cruz Biotechnology
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A cyclase III CRISPR Activation Plasmid (h) - sc-400407-ACT from Santa Cruz Biotechnology
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A cyclase III CRISPR Activation Plasmid (h2) - sc-400407-ACT-2 from Santa Cruz Biotechnology
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A cyclase III Lentiviral Activation Particles (h) - sc-400407-LAC from Santa Cruz Biotechnology
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A cyclase III Lentiviral Activation Particles (h2) - sc-400407-LAC-2 from Santa Cruz Biotechnology
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A cyclase III siRNA (h) - sc-29600 from Santa Cruz Biotechnology
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A cyclase III shRNA Plasmid (h) - sc-29600-SH from Santa Cruz Biotechnology
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A cyclase III shRNA (h) Lentiviral Particles - sc-29600-V from Santa Cruz Biotechnology
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Adenylate Cyclase 3 RNAi - H00000109-R01 from Novus Biologicals
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MISSION® esiRNA - EHU018411 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2862 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2862 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12408 from Sigma-Aldrich
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ADCY3 siRNA (Human) - CRH0072 from Cohesion Biosciences
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ADCY3 - MBS8214790 from MyBioSource
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A cyclase III CRISPR/Cas9 KO Plasmid (h2) - sc-400407-KO-2 from Santa Cruz Biotechnology
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A cyclase III HDR Plasmid (h2) - sc-400407-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human ADCY3 (NM_004036.3) - SHH232194 from Creative biogene
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Human ADCY3 siRNA - orb260574 from Biorbyt
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ADCY3 shRNA Plasmid (Human) - CHH0072 from Cohesion Biosciences
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ADCY3 miRNA 3'UTR clone - MiUTR1H-00185 from Creative biogene
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