Gene Symbol | POMC |
---|---|
Entrez Gene | 5443 |
Alt Symbol | ACTH, CLIP, LPH, MSH, NPP, POC |
Species | Human |
Gene Type | protein-coding |
Description | proopiomelanocortin |
Other Description | adrenocorticotropic hormone|adrenocorticotropin|alpha-MSH|alpha-melanocyte-stimulating hormone|beta-LPH|beta-MSH|beta-endorphin|beta-melanocyte-stimulating hormone|corticotropin-like intermediary peptide|corticotropin-lipotropin|gamma-LPH|gamma-MSH|lipotropin beta|lipotropin gamma|melanotropin alpha|melanotropin beta|melanotropin gamma|met-enkephalin|opiomelanocortin prepropeptide|pro-ACTH-endorphin|pro-opiomelanocortin|proopiomelanocortin preproprotein |
Swissprots | P78442 P01189 Q9UD40 Q53T23 Q9UD39 |
Accessions | AAB59621 AAY24354 AFV77533 AFV77534 AFV77535 AFV77536 AFV77537 AFV77538 AFV77539 AFV77540 AFV77541 AFV77542 AFV77543 AFV77544 AFV77545 AFV77546 AFV77547 AFV77548 AFV77549 AFV77550 AFV77551 AFV77552 CAA24754 EAX00729 EAX00730 P01189 AI341269 AW951218 BC065832 AAH65832 BT019918 AAV38721 CB988233 CR541826 CAG46625 DQ884404 ABI63371 M25896 AAA35799 M28636 AAA60139 M38297 AAA60140 S76492 AAC60644 XM_011532917 XP_011531219 NM_000939 NP_000930 NM_001035256 NP_001030333 |
Function | Beta-endorphin and Met-enkephalin are endogenous opiates. |
Subcellular Location | Secreted. |
Tissue Specificity | ACTH and MSH are produced by the pituitary gland. |
Top Pathways | Melanogenesis, Adipocytokine signaling pathway |
POMC CRISPR/Cas9 KO Plasmid (h) - sc-400592 from Santa Cruz Biotechnology
|
||||||||
POMC HDR Plasmid (h) - sc-400592-HDR from Santa Cruz Biotechnology
|
||||||||
POMC Double Nickase Plasmid (h) - sc-400592-NIC from Santa Cruz Biotechnology
|
||||||||
POMC Double Nickase Plasmid (h2) - sc-400592-NIC-2 from Santa Cruz Biotechnology
|
||||||||
POMC CRISPR Activation Plasmid (h) - sc-400592-ACT from Santa Cruz Biotechnology
|
||||||||
POMC CRISPR Activation Plasmid (h2) - sc-400592-ACT-2 from Santa Cruz Biotechnology
|
||||||||
POMC Lentiviral Activation Particles (h) - sc-400592-LAC from Santa Cruz Biotechnology
|
||||||||
POMC Lentiviral Activation Particles (h2) - sc-400592-LAC-2 from Santa Cruz Biotechnology
|
||||||||
POMC siRNA (h) - sc-37277 from Santa Cruz Biotechnology
|
||||||||
POMC shRNA Plasmid (h) - sc-37277-SH from Santa Cruz Biotechnology
|
||||||||
POMC shRNA (h) Lentiviral Particles - sc-37277-V from Santa Cruz Biotechnology
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN17146 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17146 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR01082 from Sigma-Aldrich
|
||||||||
POMC siRNA (Human) - CRH3646 from Cohesion Biosciences
|
||||||||
POMC RNAi - H00005443-R02 from Novus Biologicals
|
||||||||
POMC RNAi - H00005443-R01 from Novus Biologicals
|
||||||||
shRNA set against Human POMC (NM_000939.2) - SHH379717 from Creative biogene
|
||||||||
shRNA set against Human POMC(NM_000939.2) - SHR128496 from Creative biogene
|
||||||||
POMC CRISPR/Cas9 KO Plasmid (h2) - sc-400592-KO-2 from Santa Cruz Biotechnology
|
||||||||
POMC HDR Plasmid (h2) - sc-400592-HDR-2 from Santa Cruz Biotechnology
|
||||||||
Human POMC siRNA - orb264148 from Biorbyt
|
||||||||
POMC shRNA Plasmid (Human) - CHH3646 from Cohesion Biosciences
|
||||||||
POMC miRNA 3'UTR clone - MiUTR1H-08087 from Creative biogene
|
||||||||
POMC miRNA 3'UTR clone - MiUTR4H-TG06881 from Creative biogene
|