CTSB

Gene Symbol CTSB
Entrez Gene 1508
Alt Symbol APPS, CPSB
Species Human
Gene Type protein-coding
Description cathepsin B
Other Description APP secretase|amyloid precursor protein secretase|cathepsin B1|cysteine protease
Swissprots B3KRR5 B3KQR5 Q503A6 Q96D87 P07858
Accessions AAL99368 AAL99369 EAW65630 EAW65631 EAW65632 EAW65633 EAW65634 EAW65635 EAW65636 P07858 AK075393 BAG52127 AK092070 BAG52477 AK097384 BAG53460 AK098296 AK128472 AK130184 AK290239 BAF82928 AK296845 BAG59411 AK297687 BAG60046 AL543654 BC010240 AAH10240 BC095408 AAH95408 BG770805 BM008741 BX647765 CAI46053 BX647952 BX648239 CB997355 L16510 AAC37547 L38712 M13230 AAA52125 M14221 AAA52129 Y18460 CAA77178 XM_006716244 XP_006716307 XM_006716245 XP_006716308 XM_011543812 XP_011542114 NM_001908 NP_001899 NM_147780 NP_680090 NM_147781 NP_680091 NM_147782 NP_680092 NM_147783 NP_680093
Function Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
Subcellular Location Lysosome. Melanosome. Secreted, extracellular space {ECO:0000250}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways Lysosome, Antigen processing and presentation

Cathepsin B (H190) Antibody (Mouse Preferred) - 3383 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using Cathepsin B (H190) Antibody.

Cathepsin B (G60) Antibody - 3373 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from secreted protein from HL-60 cells, untreated or treated overnight with TPA #9905 (20 nM), using Cathepsin B (G60) Antibody.

cathepsin B (FL-339) - sc-13985 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
cathepsin B (FL-339): sc-13985. Western blot analysis of cathepsin B expression in LS1034 (A) and WI 38 (B) whole cell lysate.

cathepsin B (H-5) - sc-365558 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
cathepsin B (H-5): sc-365558. Western blot analysis of cathepsin B expression in WI 38 whole cell lysate.

cathepsin B (S-12) - sc-6493 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
cathepsin B (S-12): sc-6493. Western blot analysis of cathepsin B expression in LS1034 whole cell lysate.

cathepsin B (C-19)-R - sc-6490-R from Santa Cruz Biotechnology

Prices $61.00
Sizes 100 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
cathepsin B (C-19)-R: sc-6490-R. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bronchus tissue showing cytoplasmic staining of respiratory epithelial cells.

cathepsin B (CB131) - sc-58333 from Santa Cruz Biotechnology

Prices $279.00
Sizes 250 µl supernatant
Host Mouse
Clonality Monoclonal

Anti-Cathepsin B antibody - ab30443 from Abcam

Prices $373.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Cathepsin B antibody - ab190077 from Abcam

Prices $384.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-Cathepsin B antibody (ab190077) at 1/1000 dilution + Y79 cell lysate at 35 µg

Anti-Cathepsin B antibody - ab92955 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cathepsin B antibody (ab92955) at 1 µg/mlLane 1 : Liver (Human) Tissue Lysate - adult normal tissue (ab29889)Lane 2 : Kidney (Human) Tissue Lysate - adult normal tissue (ab30203)Lane 3 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466)Lane 4 : Placenta (Human) Tissue Lysate - adult normal tissue (ab29745)Lane 5 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lane 6 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Cathepsin B antibody - ab134686 from Abcam

Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human brain tissue labelling Cathepsin B with ab134686 at 1/50 dilution.

Anti-Cathepsin B antibody - ab49231 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cathepsin B antibody (ab49231) at 1/1000 dilutionLane 1 : Recombinant Human Cathepsin B at 0.04 µgLane 2 : Recombinant Human Cathepsin B at 0.02 µgLane 3 : Recombinant Human Cathepsin B at 0.01 µgLane 4 : Recombinant Human Cathepsin B at 0.004 µgLane 5 : Recombinant Human Cathepsin B at 0.002 µg

Anti-Cathepsin B antibody - ab211 from Abcam

Prices $359.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal

Anti-Cathepsin B antibody [CB131] - ab26395 from Abcam

Prices $376.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone CB131

Anti-Cathepsin B antibody [EPR4323] - ab125067 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4323
All lanes : Anti-Cathepsin B antibody [EPR4323] (ab125067) at 1/1000 dilutionLane 1 : HT1080 cell lysate Lane 2 : A375 cell lysateLane 3 : SW480 cell lysate Lane 4 : A549 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-Rabbit HRP at 1/2000 dilutiondeveloped using the ECL technique

Anti-Cathepsin B antibody [MM0126-1J37] - ab97722 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone MM0126-1J37

Anti-Cathepsin B antibody - Catalytic domain - ab49232 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cathepsin B antibody - Catalytic domain (ab49232) at 1/1000 dilutionLane 1 : Recombinant Human Cathepsin B at 0.04 µgLane 2 : Recombinant Human Cathepsin B at 0.02 µgLane 3 : Recombinant Human Cathepsin B at 0.01 µgLane 4 : Recombinant Human Cathepsin B at 0.004 µgLane 5 : Recombinant Human Cathepsin B at 0.002 µg

Anti-CTSB / Cathepsin B Antibody - LS-C21357 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTSB / Cathepsin B Antibody - LS-C21360 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTSB / Cathepsin B Antibody - LS-C21358 from LifeSpan Bioscience

Host Sheep
Clonality Polyclonal

Anti-CTSB / Cathepsin B Antibody (clone CB 59-4B11) - LS-C21362 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CTSB / Cathepsin B Antibody - LS-C85753 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTSB / Cathepsin B Antibody - LS-C42674 from LifeSpan Bioscience

Host Sheep
Clonality Polyclonal

Anti-CTSB / Cathepsin B Antibody - LS-C77980 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CTSB / Cathepsin B Antibody (HRP) - LS-C124926 from LifeSpan Bioscience

Host Sheep
Clonality Polyclonal
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