Gene Symbol | BBS12 |
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Entrez Gene | 166379 |
Alt Symbol | C4orf24 |
Species | Human |
Gene Type | protein-coding |
Description | Bardet-Biedl syndrome 12 |
Other Description | Bardet-Biedl syndrome 12 protein |
Swissprots | Q7Z342 Q8NAB8 Q7Z482 D3DNX5 Q6ZW61 |
Accessions | EAX05223 EAX05224 Q6ZW61 AK092949 BAC04006 AK123553 BAC85644 BC055426 AAH55426 BC065708 BX538148 CAD98035 CD359068 XM_011531680 XP_011529982 NM_001178007 NP_001171478 NM_152618 NP_689831 |
Function | Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation. {ECO:0000269|PubMed:19190184, ECO:0000269|PubMed:20080638}. |
Subcellular Location | Cell projection, cilium {ECO:0000269|PubMed:19190184}. Note=Located within the basal body of the primary cilium of differentiating preadipocytes. |
BBS12 CRISPR/Cas9 KO Plasmid (h) - sc-416560 from Santa Cruz Biotechnology
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BBS12 HDR Plasmid (h) - sc-416560-HDR from Santa Cruz Biotechnology
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BBS12 Double Nickase Plasmid (h) - sc-416560-NIC from Santa Cruz Biotechnology
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BBS12 Double Nickase Plasmid (h2) - sc-416560-NIC-2 from Santa Cruz Biotechnology
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BBS12 CRISPR Activation Plasmid (h) - sc-416560-ACT from Santa Cruz Biotechnology
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BBS12 CRISPR Activation Plasmid (h2) - sc-416560-ACT-2 from Santa Cruz Biotechnology
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BBS12 Lentiviral Activation Particles (h) - sc-416560-LAC from Santa Cruz Biotechnology
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BBS12 Lentiviral Activation Particles (h2) - sc-416560-LAC-2 from Santa Cruz Biotechnology
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BBS12 siRNA (h) - sc-88923 from Santa Cruz Biotechnology
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BBS12 shRNA Plasmid (h) - sc-88923-SH from Santa Cruz Biotechnology
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BBS12 shRNA (h) Lentiviral Particles - sc-88923-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU004381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3879 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3879 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07432 from Sigma-Aldrich
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BBS12 siRNA (Human) - CRJ6041 from Cohesion Biosciences
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BBS12 - MBS8215126 from MyBioSource
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shRNA set against Human BBS12 (NM_152618.2) - SHH245130 from Creative biogene
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shRNA set against Human BBS12(NM_152618.2) - SHG092135 from Creative biogene
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Human BBS12 siRNA - orb276542 from Biorbyt
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BBS12 shRNA Plasmid (Human) - CHJ6041 from Cohesion Biosciences
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BBS12 miRNA 3'UTR clone - MiUTR1H-00824 from Creative biogene
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